European Journal of Obstetrics & Gynecology and Reproductive Biology
Volume 134, Issue 1 , Pages 24-28, September 2007

Biochemical determinations of arylsulphatase A activity and sulphatide concentrations in decidua of women at 41 and 42 weeks of gestation

  • Emilia Baldoni

      Affiliations

    • Department of Comparative Morphological and Biochemical Sciences, University of Camerino, Camerino, Italy
    • Corresponding Author InformationCorresponding author. Tel.: +39 0737402706; fax: +39 0737402709.
  • ,
  • Enea Traini

      Affiliations

    • Department of Comparative Morphological and Biochemical Sciences, University of Camerino, Camerino, Italy
  • ,
  • Daniele Tomassoni

      Affiliations

    • Section of Human Anatomy, Department of Pharmacological Sciences and Experimental Medicine, University of Camerino, Camerino, Italy
  • ,
  • Ugo Indraccolo

      Affiliations

    • Department of Obstetrics, Gynaecology and Pediatrics Sciences, University of Perugia, Italy
  • ,
  • S. Renato Indraccolo

      Affiliations

    • Department of Gynaecology, Perinatology and Child Welfare, II Faculty of Medicine and Surgery, “La Sapienza” University, Rome, Italy
  • ,
  • Lucia Vitaioli

      Affiliations

    • Department of Comparative Morphological and Biochemical Sciences, University of Camerino, Camerino, Italy

Received 13 December 2005; received in revised form 6 August 2006; accepted 15 September 2006. published online 10 October 2006.

Abstract 

Objective

To evaluate arylsulphatase A activity and sulphatide concentrations in decidua of women at 41 and 42 weeks of gestation.

Study design

Enzyme activity and sulphatide concentrations were determined by biochemical procedures on samples of women at 41 and 42 weeks of gestation; thin-layer chromatography was also prepared to separate and visualize sulphatides and other lipid fractions.

Results

The spectrophotometric values of arylsulphatase A showed very low values at 41 weeks, which reduced to a half at 42 weeks of gestation, while values of sulphatide concentrations increased in 42 weeks.

Conclusions

The behavior of two parameters examined could be due to the amount of placental estriol reduction, because of sudden placental aging.

Keywords: Arylsulphatase A, Sulphatides, Decidua, Prolonged gestation

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PII: S0301-2115(06)00511-2

doi:10.1016/j.ejogrb.2006.09.007

European Journal of Obstetrics & Gynecology and Reproductive Biology
Volume 134, Issue 1 , Pages 24-28, September 2007