European Journal of Obstetrics & Gynecology and Reproductive Biology
Volume 136, Issue 2 , Pages 146-150, February 2008

The role of leptin in fetal growth: A short review from conception to delivery

  • Sorina Grisaru-Granovsky

      Affiliations

    • Department of Obstetrics and Gynecology, Shaare Zedek Medical Center, Jerusalem, Israel
    • ,
  • Arnon Samueloff

      Affiliations

    • Department of Obstetrics and Gynecology, Shaare Zedek Medical Center, Jerusalem, Israel
    • ,
  • Deborah Elstein

      Affiliations

    • Gaucher Clinic, Shaare Zedek Medical Center, Jerusalem 91031, Israel
    • Corresponding Author InformationCorresponding author. Tel.: +972 2 6555093; fax: +972 2 6517979.

Received 21 January 2007; received in revised form 13 June 2007; accepted 16 June 2007. published online 28 July 2007.

Abstract 

Abnormally high- or low-serum maternal levels and/or levels in placental, umbilical blood, and fetus/neonate are associated with a wide spectrum of complicated pregnancies. Whereas the state of knowledge about mechanisms and pathways involving secondary or tertiary modulators is far from complete, the role of leptin from ovulation and implantation and throughout pregnancy underscores its importance in normal and abnormal states.

Keywords: Adipokines, Conception, Fertility, Intrauterine growth failure, Leptin, Pre-eclampsia, Pregnancy, Reproduction

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PII: S0301-2115(07)00314-4

doi:10.1016/j.ejogrb.2007.06.021

European Journal of Obstetrics & Gynecology and Reproductive Biology
Volume 136, Issue 2 , Pages 146-150, February 2008

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