European Journal of Obstetrics & Gynecology and Reproductive Biology
Volume 143, Issue 2 , Pages 112-115 , April 2009

Successful treatment of refractory endometriosis-related chronic pelvic pain with aromatase inhibitors in premenopausal patients

  • Alka Verma

      Affiliations

    • Women's Hospital, Leicester Royal Infirmary, Leicester LE1 5WW, UK
  • ,
  • Justin C. Konje

      Affiliations

    • Reproductive Science Section, Department of Cancer Studies and Molecular Medicine, University of Leicester, Robert Kilpatrick Clinical Sciences Building, Leicester LE2 7LX, UK
    • Corresponding Author InformationCorresponding author.

Received 5 June 2008 ,Revised 3 December 2008 ,Accepted 29 December 2008.

References 

  1. Amsterdam LL, Gentry W, Jobanputra S, Wolf M, Rubin SD, Bulun SE. Anastrazole and oral contraceptives: a novel treatment for endometriosis. Fertil Steril. 2005;84:300–304
  2. Cottreau CM, Ness RB, Modugno F, Allen GO, Goodman MT. Endometriosis and its treatment with danazol or lupron in relation to ovarian cancer. Clin Cancer Res. 2003;9:5142–5244
  3. Takayama K, Zeitoun K, Gunby RT, Sasano H, Carr BR, Bulun SE. Treatment of severe postmenopausal endometriosis with an aromatase inhibitor. Fertil Steril. 1998;69:709–713
  4. Abbott JA, Hawe J, Clayton RD, Garry R. The effects and effectiveness of laparoscopic excision of endometriosis: a prospective study with 2–5 year follow up. Hum Reprod. 2003;18:1922–1927
  5. Lockhat FB, Emembolu JO, Konje JC. The efficacy, side-effects and continuation rates in women with symptomatic endometriosis undergoing treatment with an intra-uterine administered progestrogen (levonorgestrel): a 3 year follow-up. Hum Reprod. 2005;20:789–793
  6. The American Fertility Society . Revised American fertility society classification of endometriosis. Fertil Steril. 1985;43:351
  7. Attar E, Bulun SE. Aromatase inhibitors: the next generation of therapeutics for endometriosis?. Fertil Steril. 2006;85:1307–1318
  8. Razzi S, Fava A, Sartini A, De Simone S, Ccbellis L, Petraglia F. Treatment of severe recurrent endometriosis with an aromatase inhibitor in a young ovariectomised women. BJOG. 2004;111:182–184
  9. Santen RJ, Samojlik E, Wells SA. Resistance of the ovary to blockade of aromatisation with aminoglutethimide. J Clin Endocrinol Metab. 1980;51:473–477
  10. Wanders HE, Blossey HC, Nagel GA. Aminoglutethimide in the treatment of premenopausal patients with metastatic breast cancer. Eur J Cancer Clin Oncol. 1986;22:1371–1374
  11. Shippen ER, William JW. Successful treatment of severe endometriosis in two premenopausal women with an aromatase inhibitor. Fertil Steril. 2004;81:1395–1398
  12. Soysal S, Soysal M, Ozer S, Gul N, Gezgin T. The effects of post surgical administration of goserelin plus anastrazole compared to goserelin alone in patients with severe endometriosis: a prospective randomised trial. Hum Reprod. 2004;19:160–167
  13. Ailawadi RK, Jobanputra S, Kataria M, Gurates B, Bulun SE. Treatment of endometriosis and chronic pelvic pain with letrozole and norethindrone acetate: a pilot study. Fertil Steril. 2004;81:290–296
  14. Geisler J, Haynes B, Anker G, et al. Influence of letrozole and anastrozole on total body aromatization and plasma estrogen levels in postmenopausal breast cancer patients evaluated in a randomized, cross-over study. J Clin Oncol. 2002;20:751–757

PII: S0301-2115(09)00011-6

doi: 10.1016/j.ejogrb.2008.12.002

European Journal of Obstetrics & Gynecology and Reproductive Biology
Volume 143, Issue 2 , Pages 112-115 , April 2009