European Journal of Obstetrics & Gynecology and Reproductive Biology
Volume 144, Issue 1 , Pages 35-39 , May 2009

Multiplex fluorescent PCR for noninvasive prenatal detection of fetal-derived paternally inherited diseases using circulatory fetal DNA in maternal plasma

  • Tang Dong-ling

      Affiliations

    • Department of Clinical Laboratory, Renmin Hospital of Wuhan University, Ziyang Road 99, Wuhan, 430060, Hubei Province, PR China
    • Corresponding Author InformationCorresponding authors. Tel.: +86 27 62428926; fax: +86 27 88042292.
    • ,
  • Li Yan

      Affiliations

    • Department of Clinical Laboratory, Renmin Hospital of Wuhan University, Ziyang Road 99, Wuhan, 430060, Hubei Province, PR China
    • Corresponding Author InformationCorresponding authors. Tel.: +86 27 62428926; fax: +86 27 88042292.
    • ,
  • Zhou Xin

      Affiliations

    • Department of Clinical Laboratory, Zhongnan Hospital of Wuhan University, Wuhan, 430071, PR China
    • ,
  • Li Xia

      Affiliations

    • Department of Clinical Laboratory, Zhongnan Hospital of Wuhan University, Wuhan, 430071, PR China
    • ,
  • Zheng Fang

      Affiliations

    • Department of Clinical Laboratory, Zhongnan Hospital of Wuhan University, Wuhan, 430071, PR China

Received 28 April 2008 ,Revised 28 December 2008 ,Accepted 1 February 2009.

References 

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  14. Ding C, Chiu RW, Lau TK, et al. MS analysis of single-nucleotide differences in circulating nucleic acids: application to noninvasive prenatal diagnosis. Proc Natl Acad Sci. 2004;101(29):10762–10767
  15. Tsujie T, Takemura M, Kimura T, et al. Rapid detection of trisomy 21 by gene dosage analysis using quantitative real-time polymerase chain reaction. J Obstet Gynaecol Res. 2006;32:368–372
  16. Eroglu D, Yanik F, Sakallioglu AE, Arikan U, Varan B, Kuscu E. Prenatal diagnosis of bilateral diaphragmatic hernia by fetal sonography. J Obstet Gynaecol Res. 2006;32(1):90–93
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PII: S0301-2115(09)00089-X

doi: 10.1016/j.ejogrb.2009.02.002

European Journal of Obstetrics & Gynecology and Reproductive Biology
Volume 144, Issue 1 , Pages 35-39 , May 2009

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