European Journal of Obstetrics & Gynecology and Reproductive Biology
Volume 147, Issue 2 , Pages 157-160, December 2009

Contribution and limit of the model of perfused cotyledon to the study of placental transfer of drugs. Example of a protease inhibitor of HIV: Nelfinavir

  • Laurent Gavard

      Affiliations

    • Department of Clinical Pharmacy, University Paris-Sud 11, IFR141, School of Pharmacy, Châtenay-Malabry, France
    • Department of Obstetrics and Gynecology, AP-HP, Louis Mourier Hospital, University Denis Diderot Paris 7, Colombes, France
    • Corresponding Author InformationCorresponding author at: Faculté de Pharmacie – UPRES EA 2706, Laboratoire de Pharmacie Clinique, 5 rue Jean Baptiste Clément, 92296 Châtenay-Malabry cedex 20, France. Tel.: +33 01 4683 5577; fax: +33 01 4683 5618.
    • ,
  • Delphine Beghin

      Affiliations

    • Department of Clinical Pharmacy, University Paris-Sud 11, IFR141, School of Pharmacy, Châtenay-Malabry, France
    • ,
  • François Forestier

      Affiliations

    • Department of Clinical Pharmacy, University Paris-Sud 11, IFR141, School of Pharmacy, Châtenay-Malabry, France
    • ,
  • Yvon Cayre

      Affiliations

    • Robert Debré Hospital, AP-HP, University Pierre et Marie Curie - Paris 6, UMR 7613 Synthèse, Structure et Fonction de Molécules Bioactives, Paris, France
    • ,
  • Gilles Peytavin

      Affiliations

    • Department of Pharmacology, AP-HP, Bichat Hospital, University Denis Diderot - Paris 7, Paris, France
    • ,
  • Laurent Mandelbrot

      Affiliations

    • Department of Obstetrics and Gynecology, AP-HP, Louis Mourier Hospital, University Denis Diderot Paris 7, Colombes, France
    • ,
  • Robert Farinotti

      Affiliations

    • Department of Clinical Pharmacy, University Paris-Sud 11, IFR141, School of Pharmacy, Châtenay-Malabry, France
    • Department of pharmacology, AP-HP, Pitié-Salpêtrière Hospital, University Pierre et Marie Curie - Paris 6, Paris, France
    • ,
  • Sophie Gil

      Affiliations

    • Department of Clinical Pharmacy, University Paris-Sud 11, IFR141, School of Pharmacy, Châtenay-Malabry, France

Received 21 January 2009; received in revised form 1 July 2009; accepted 18 August 2009. published online 01 September 2009.

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PII: S0301-2115(09)00496-5

doi:10.1016/j.ejogrb.2009.08.007

European Journal of Obstetrics & Gynecology and Reproductive Biology
Volume 147, Issue 2 , Pages 157-160, December 2009

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