European Journal of Obstetrics & Gynecology and Reproductive Biology
Volume 148, Issue 2 , Pages 177-181 , February 2010

Clinical and morphological factors predictive of occult involvement of the nipple-areola complex in mastectomy specimens

  • Paulo R. Pirozzi

      Affiliations

    • ABC School of Medicine, Av. Príncipe de Gales, 821, Santo André 09060-650, SP, Brazil
    • ,
  • Claudia Rossetti

      Affiliations

    • ABC School of Medicine, Av. Príncipe de Gales, 821, Santo André 09060-650, SP, Brazil
    • ,
  • Ivo Carelli

      Affiliations

    • ABC School of Medicine, Av. Príncipe de Gales, 821, Santo André 09060-650, SP, Brazil
    • ,
  • Carlos A. Ruiz

      Affiliations

    • São Paulo University School of Medicine, Av. Dr. Arnaldo, 455, São Paulo 01246-903, SP, Brazil
    • ,
  • Luciano M. Pompei

      Affiliations

    • ABC School of Medicine, Av. Príncipe de Gales, 821, Santo André 09060-650, SP, Brazil
    • Corresponding Author InformationCorresponding author at: Rua Dona Adma Jafet 74, cj. 51, Sao Paulo 01308-050, SP, Brazil. Tel.: +55 11 3259 0005; fax: +55 11 2548 3316.
    • ,
  • Sebastião Piato

      Affiliations

    • Santa Casa de São Paulo School of Medical Sciences, Rua Dr. Cesário Motta Jr., 61, São Paulo 01221-020, SP, Brazil

Received 4 May 2009 ,Revised 28 September 2009 ,Accepted 19 October 2009.

References 

  1. Gerber B, Krause A, Reimer T, et al. Skin-sparing mastectomy with conservation of the nipple-areola complex and autologous reconstruction is an oncologically safe procedure?. Ann Surg. 2003;238:120–127
  2. Crowe JP, Kim JA, Yetman R, Banbury J, Patrick RJ, Baynes D. Nipple-sparing mastectomy: technique and results of 54 procedures. Arch Surg. 2004;139:148–150
  3. Fersis N, Hoenig A, Relakis K, Pinis S, WallwIener D. Skin-sparing mastectomy and immediate breast reconstruction: incidence of recurrence in patients with invasive breast cancer. Breast. 2004;13:488–493
  4. Wellings SR. A hypothesis of the origin of human breast cancer from the terminal ductal lobular unit. Pathol Res Pract. 1980;166:515–535
  5. Jensen JA. When can the nipple-areola complex safely be spared during mastectomy?. Plast Reconstr Surg. 2002;109:805–807
  6. Laronga C, Kemp B, Johnston D, Robb GL, Singletary SE. The incidence of occult nipple-areola complex involvement in breast cancer patients receiving a skin-sparing mastectomy. Ann Surg Oncol. 1999;6:609–613
  7. Caruso F, Ferrara M, Castiglione G, et al. Nipple sparing subcutaneous mastectomy: sixty-six months follow-up. Eur J Surg Oncol. 2006;32:937–940
  8. Benediktsson KP, Perbeck L. Survival in breast cancer after nipple-sparing subcutaneous mastectomy and immediate reconstruction with implants: a prospective trial with 13 years median follow-up in 216 patients. Eur J Surg Oncol. 2008;34:143–148
  9. Vlajcic Z, Zic R, Stanec S, Lambasa S, Petrovecki M, Stanec Z. Nipple-areola complex preservation: predictive factors of neoplastic nipple-areola complex invasion. Ann Plast Surg. 2005;55:240–244
  10. Schecter AK, Fremman MB, Giri D, Sabo E, Weinzweig J. Applicability of the nipple-areola complex-sparing mastectomy: a prediction model using mammography to estimate risk of nipple-areola complex involvement in breast cancer patients. Ann Plast Surg. 2006;56:498–504
  11. Loewen MJ, Jennings JA, Sherman SR, et al. Mammographic distance as a predictor of nipple-areola complex involvement in breast cancer. Am J Surg. 2008;195:391–395
  12. Lambert PA, Kolm P, Perry RR. Parameters that predict nipple involvement in breast cancer. J Am Coll Surg. 2000;191:354–359
  13. Vyas JJ, Chinoy RF, Vaidya JS. Prediction of nipple and areola involvement in breast cancer. Eur J Surg Oncol. 1998;24:15–16
  14. Dzierzanowski M, Melville KA, Barnes PJ, Macintosh RF, Caines JS, Porter GA. Ductal carcinoma in situ in core biopsies containing invasive breast cancer: correlation with extensive intraductal component and lumpectomy margins. J Surg Oncol. 2005;90:71–76
  15. Elston CW, Ellis IO. Pathological prognostic factors in breast câncer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up. Histopathology. 1991;19:403–410
  16. Dabbs DJ. Ductal carcinoma of breast: nuclear grade as a predictor of S-phase fraction. Hum Pathol. 1993;24:652–656
  17. Kissin MW, Kark AE. Nipple preservation during mastectomy. Br J Surg. 1987;74:58–61
  18. Bishop CC, Singh S, Nash AG. Mastectomy and breast reconstruction preserving the nipple. Ann R Coll Surg Engl. 1990;72:87–89
  19. Hashimoto BE, Morgan GN, Kramer DJ, Lee M. Systematic approach to difficult problems in breast sonography. Ultrasound Q. 2008;24(1):31–38
  20. Cooney CS, Khouri NF, Tsangaris TN. The role of breast MRI in the management of patients with breast disease. Adv Surg. 2008;42:299–312
  21. Katipamula R, Degnim AC, Hoskin T, et al. Trends in mastectomy rates at the Mayo Clinic Rochester: effect of surgical year and preoperative magnetic resonance imaging. J Clin Oncol. 2009;27(25):4082–4088
  22. Bleicher RJ, Ciocca RM, Egleston BL, et al. Association of routine pretreatment magnetic resonance imaging with time to surgery, mastectomy rate, and margin status. J Am Coll Surg. 2009;209(2):180–187
  23. Schell AM, Rosenkranz K, Lewis PJ. Role of breast MRI in the preoperative evaluation of patients with newly diagnosed breast cancer. AJR Am J Roentgenol. 2009;192(5):1438–1444
  24. Siegmann KC, Baur A, Vogel U, et al. Risk-benefit analysis of preoperative breast MRI in patients with primary breast cancer. Clin Radiol. 2009;64(4):403–413
  25. Pediconi F, Catalano C, Roselli A, et al. The challenge of imaging dense breast parenchyma: is magnetic resonance mammography the technique of choice? A comparative study with X-ray mammography and whole-breast ultrasound. Invest Radiol. 2009;44(7):412–421
  26. Lehman CD, DeMartini W, Anderson BO, Edge SB. Indications for breast MRI in the patient with newly diagnosed breast cancer. J Natl Compr Canc Netw. 2009;7(2):193–201

PII: S0301-2115(09)00637-X

doi: 10.1016/j.ejogrb.2009.10.021

European Journal of Obstetrics & Gynecology and Reproductive Biology
Volume 148, Issue 2 , Pages 177-181 , February 2010

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