European Journal of Obstetrics & Gynecology and Reproductive Biology
Volume 151, Issue 1 , Pages 91-95 , July 2010

A pilot study comparing efficacy of a cervical intraepithelial neoplasia excisor with loop electrosurgical excision procedure

  • Olaleye Sanu

      Affiliations

    • Department of Obstetrics and Gynaecology, St Marys Imperial College NHS Trust, London W2, United Kingdom
    • Corresponding Author InformationCorresponding author. Fax: +44 2084207466.
    • ,
  • Alak Pal

      Affiliations

    • Department of Obstetrics and Gynaecology, Colposcopy Services, Ealing Hospital, NHS Trust, Uxbridge Road, Southall, Middlesex, UB1 3HW, United Kingdom
    • ,
  • Samuel George

      Affiliations

    • Department of Obstetrics and Gynaecology, Colposcopy Services, Ealing Hospital, NHS Trust, Uxbridge Road, Southall, Middlesex, UB1 3HW, United Kingdom

Received 17 October 2009 ,Revised 18 January 2010 ,Accepted 21 February 2010.

References 

  1. Prendiville W, Cullimore J, Norman S. Large loop excision of the transformation zone (LLETZ). A new method of management for women with cervical intraepithelial neoplasia. Br J Obstet Gynaecol. 1989;96:1054–1060
  2. Keijser KGG, Kenemans P, Van der Zanden PHTH, Schijf CPT, Vooijis GP, Rolland R. Diathermy loop excision in the management of cervical intraepithelial neoplasia: diagnosis and treatment in one procedure. Am J Obstet Gynecol. 1992;166:1281–1287
  3. Luesley DM, Cullimore J, Redman CW, et al. Loop diathermy excision of the cervical transformation zone in patients with abnormal cervical smears. BMJ. 1990;300:1690–1693
  4. Livasy CA, Maygarden SJ, Rajaratnam CT, Novotny DB. Predictors of recurrent dysplasia after cervical loop electrocautery excision procedure for CIN-3: a study of margin, endocervical gland, and quadrant involvement. Mod Pathol. 1999;12:233–238
  5. Zaitoun AM, McKee G, Coppen MJ, Thomas SM, Wilson POG. Completeness of excision and follow up cytology in patients treated with loop excision biopsy. J Clin Pathol. 2000;53:191–196
  6. Saenz de Cabezon RHY, Sala CV, Gomis SS, Lliso AR, Bellvert CG. Evaluation of cervical dysplasia treatment by large loop excision of the transformation zone (LLETZ): does completeness of excision determine outcome?. Eur J Obstet Gynecol Reprod Biol. 1998;78:83–87
  7. Dobbs SP, Asmussen T, Nunns D, Hollingworth J, Brown LJR, Ireland D. Does histological incomplete excision of cervical intraepithelial neoplasia following large loop excision of transformation zone increase recurrence rates?. Br J Obstet Gynaecol. 2000;107:1298–1301
  8. Paraskevaidis E, Lolis ED, Koliopoulos G, Alamanos Y, Fotiou S, Kitchener HC. Cervical intraepithelial neoplasia outcomes after large loop excision with clear margins. Obstet Gynecol. 2000;95:828–831
  9. Luesley D, Leeson S, editors. Colposcopy and programme management: guidelines for the NHS cervical screening programme. NHSCSP Publication No. 20; 2004.
  10. Boardman LA, Steinhoff MM, Shackelton R, Weitzzen S, Crowthers L. A randomised trial of the Fischer cone biopsy excisor and loop electrosurgical excision procedure. Obstet Gynecol. 2004;104:745–750
  11. Kreuger FAF, Beerman H, Nijs HGT, Van Ballegooijen M. Positive diagnostic values and histological detection ratios from the Rotterdam cervical cancer screening programme. Int J Epidemiol. 1998;27:377–381
  12. Ostor AG. Natural history of cervical intraepithelial neoplasia. Int J Gynecol Pathol. 1993;12:186
  13. Paraskevaidis E, Koliopoulos G, Malamou-Mitsi V, et al. Large loop excision of the transformation zone for treating cervical intraepithelial neoplasia: a 12-year experience. Anticancer Res. 2001;21:3097–3099
  14. Flannelly G, Bolger B, Fawzi H, De Lopes AB, Monaghan JM. Follow up after LLETZ: could schedules be modified according to risk of recurrence?. Br J Obstet Gynaecol. 2001;108:1025–1030
  15. Paraskevaidis E, Kitchener H, Adonakis G, Parkin D, Lolis D. Incomplete excision of CIN in conization: further excision or conservative management?. Eur J Obstet Gynecol Reprod Biol. 1994;53:45–47
  16. Pardo J, Yogev Y, Ben-Haroush A, Peled Y, Kaplan B, Hod M. Cervical length evaluation by transvaginal sonography in nongravid women with a history of preterm delivery. Ultrasound Obstet Gynecol. 2003;21:464–466
  17. Panoskaltsis T, Ind TEJ, Perryman K, Dina R, Abrahams Y, Soutter WP. Needle versus loop diathermy excision of the transformation zone for the treatment of cervical intraepithelial neoplasia: a randomised controlled trial. Br J Obstet Gynaecol. 2004;111:748–753

☆ Source: Ealing Hospital NHS Trust, Uxbridge Road, Southall, Middlesex UB1 3HW, United Kingdom.

PII: S0301-2115(10)00108-9

doi: 10.1016/j.ejogrb.2010.02.042

European Journal of Obstetrics & Gynecology and Reproductive Biology
Volume 151, Issue 1 , Pages 91-95 , July 2010

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