European Journal of Obstetrics & Gynecology and Reproductive Biology
Volume 160, Issue 1 , Pages 1-5 , January 2012

Efficacy of auto-crosslinked hyaluronan gel for adhesion prevention in laparoscopy and hysteroscopy: a systematic review and meta-analysis of randomized controlled trials

  • Valerio Mais

      Affiliations

    • Division of Gynaecology, Obstetrics and Pathophysiology of Human Reproduction, Department of Surgery, Maternal–Fetal Medicine and Imaging, University of Cagliari, 09124 Cagliari, Italy
    • Corresponding Author InformationCorresponding author at: Division of Gynecology, Obstetrics and Pathophysiology of Human Reproduction, Department of Surgery, Maternal–Fetal Medicine and Imaging, University of Cagliari, Ospedale S. Giovanni di Dio, Via Ospedale 46, 09124 Cagliari, Italy. Tel.: +39 070652797; fax: +39 070668575.
  • ,
  • Maria G. Cirronis

      Affiliations

    • Division of Gynaecology, Obstetrics and Pathophysiology of Human Reproduction, Department of Surgery, Maternal–Fetal Medicine and Imaging, University of Cagliari, 09124 Cagliari, Italy
  • ,
  • Michele Peiretti

      Affiliations

    • Division of Gynaecology, European Institute of Oncology, 20141 Milano, Italy
  • ,
  • Giuliano Ferrucci

      Affiliations

    • Informa S.r.l., 00154 Roma, Italy
  • ,
  • Ester Cossu

      Affiliations

    • Division of Gynaecology, Obstetrics and Pathophysiology of Human Reproduction, Department of Surgery, Maternal–Fetal Medicine and Imaging, University of Cagliari, 09124 Cagliari, Italy
  • ,
  • Gian B. Melis

      Affiliations

    • Division of Gynaecology, Obstetrics and Pathophysiology of Human Reproduction, Department of Surgery, Maternal–Fetal Medicine and Imaging, University of Cagliari, 09124 Cagliari, Italy

Received 3 March 2011 ,Revised 12 July 2011 ,Accepted 31 August 2011.

  • Image Result

    PRISMA trial flow diagram.

    PRISMA trial flow diagram.

  • Image Result

    Forest plot showing Odds Ratio for incidence of postoperative adhesions in hysteroscopic RCTs and laparoscopic RCTs comparing application of auto-crosslinked hyaluronan gel with no application (contro

    Forest plot showing Odds Ratio for incidence of postoperative adhesions in hysteroscopic RCTs and laparoscopic RCTs comparing application of auto-crosslinked hyaluronan gel with no application (control).

PII: S0301-2115(11)00494-5

doi: 10.1016/j.ejogrb.2011.08.002

European Journal of Obstetrics & Gynecology and Reproductive Biology
Volume 160, Issue 1 , Pages 1-5 , January 2012