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Editorial Board
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iii
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Introduction
02 March 2009
Human reproduction is the outcome of a series of complex events which act in concert to produce a living offspring. These events are driven by synchronized activation of molecular and biochemical proc...
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David Elad,
Ludwig Wildt
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S1
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| Myometrial contractility and Calcium transport |
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Integration of endocrine and mechanical signals in the regulation of myometrial functions during pregnancy and labour
06 March 2009
Abstract: In this review, we describe a new model to explain the regulation of myometrial function during pregnancy and labour. We propose that the myometrium undergoes dramatic changes in phenotype f...
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Oksana Shynlova,
Prudence Tsui,
Shabana Jaffer,
Stephen J. Lye
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S2-S10
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A review of recent insights into the role of the sarcoplasmic reticulum and Ca entry in uterine smooth muscle
02 March 2009
Abstract: The uterine sacroplasmic reticulum (SR) takes up and stores calcium [Ca], using an ATPase (SERCA) and the Ca-buffering proteins, calsequestrin and calreticulin. This stored Ca can be release...
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Karen Noble,
Andy Matthew,
Theodor Burdyga,
Susan Wray
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S11-S19
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Phase-plot analysis of the oxytocin effect on human myometrial contractility
02 March 2009
Abstract: Objective: Analysis of uterine contractility in vitro is usually confined to measuring a few traditional parameters of uterine contractility, such as contraction amplitude, frequency and are...
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Joanna E. Gullam,
Andrew M. Blanks,
Steven Thornton,
Anatoly Shmygol
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S20-S24
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Temporal and spatial variations in spontaneous Ca events and mechanical activity in pregnant rat myometrium
02 March 2009
Abstract: Objectives: The aim of this study was to investigate the temporal and spatial characteristics of spontaneous Ca signals in pregnant rat myometrium. Study design: Confocal imaging of longitud...
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Theodor Burdyga,
Ludmila Borisova,
Alex T. Burdyga,
Susan Wray
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S25-S32
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Monitoring the progress of pregnancy and labor using electromyography
02 March 2009
Abstract: At present, there is no effective treatment for preterm labor. The most obvious reason for this anomaly is that there is no objective manner in which to evaluate the progression of pregnancy...
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Dietmar Schlembach,
Wiliam L. Maner,
Robert E. Garfield,
Holger Maul
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S33-S39
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A short review of twin pregnancy and how oxytocin receptor expression may differ in multiple pregnancy
02 March 2009
Abstract: During a multiple pregnancy, the mother and her fetuses are exposed to a variety of risks during both pregnancy and labour. The most notable of these risks is that of pre-term labour and its...
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Peter Turton,
James P. Neilson,
Siobhan Quenby,
Theodor Burdyga,
Susan Wray
et al.
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S40-S44
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| Uterine peristalsis |
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Uterine mechanisms of ipsilateral directed spermatozoa transport: Evidence for a contribution of the utero-ovarian countercurrent system
02 March 2009
Abstract: Objective: Spermatozoa transport into uterus and fallopian tubes is directed to the side of the dominant follicle and seems to be controlled by the ipsilateral ovary. The objective of this s...
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I. Zervomanolakis,
H.W. Ott,
J. Müller,
B.E. Seeber,
S.C. Friess,
V. Mattle,
I. Virgolini,
D. Heute,
L. Wildt
et al.
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S45-S49
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Simulation of embryo transport in a closed uterine cavity model
02 March 2009
Abstract: Objective: Uterine peristalsis is induced by synchronized contractions of the non-pregnant myometrium. The resulting periodic motions of the anterior and posterior walls of the uterus genera...
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Sarit Yaniv,
Ariel J. Jaffa,
Osnat Eytan,
David Elad
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S50-S60
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Uterine contraction signals—Application of the linear synchronization measures
02 March 2009
Abstract: Objective: In physiological research, there are not too many studies on multivariate data sets, containing two or more simultaneously recorded time series. It is important to examine synchro...
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Agnieszka Kitlas,
Edward Oczeretko,
Jolanta Świątecka,
Marta Borowska,
Tadeusz Laudański
et al.
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S61-S64
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| Biomechanics of the uterus and cervix in pregnancy |
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Magnetic resonance imaging of three-dimensional cervical anatomy in the second and third trimester
02 March 2009
Abstract: Objective: Although a short cervix is known to be associated with preterm birth, the patterns of three-dimensional, anatomic changes leading to a short cervix are unknown. Our objective was ...
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Michael House,
Rafeeque A. Bhadelia,
Kristin Myers,
Simona Socrate
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S65-S69
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Cervical ripening and insufficiency: From biochemical and molecular studies to in vivo clinical examination
02 March 2009
Abstract: To understand cervical ripening and especially the pathophysiology of cervical insufficiency, it is important to know the cervical composition: the cervix is dominated by fibrous connective ...
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Dietmar Schlembach,
Lynette MacKay,
Leili Shi,
William L. Maner,
Robert E. Garfield,
Holger Maul
et al.
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S70-S76
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Assessment of the in vivo biomechanical properties of the human uterine cervix in pregnancy using the aspiration test: A feasibility study
02 March 2009
Abstract: Objective: To date no diagnostic tool is yet available to objectively assess the in vivo biomechanical properties of the uterine cervix during gestation. Methods: We show the first clinical ...
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Margit Bauer,
Edoardo Mazza,
Mahmood Jabareen,
Leila Sultan,
Michael Bajka,
Uwe Lang,
Roland Zimmermann,
Gerhard A. Holzapfel
et al.
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S77-S81
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Changes in the biochemical constituents and morphologic appearance of the human cervical stroma during pregnancy
02 March 2009
Abstract: Objective: The cervix is the lower portion of the uterus. It is composed of fibrous tissue and its mechanical integrity is crucial for maintaining a healthy gestation. During normal pregnanc...
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Kristin Myers,
Simona Socrate,
Dimitrios Tzeranis,
Michael House
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S82-S89
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Uterus models for use in virtual reality hysteroscopy simulators
02 March 2009
Abstract: Objectives: Virtual reality models of human organs are needed in surgery simulators which are developed for educational and training purposes. A simulation can only be useful, however, if th...
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Peter Niederer,
Stephan Weiss,
Rosmarie Caduff,
Michael Bajka,
Gabor Szekély,
Matthias Harders
et al.
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S90-S95
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Extraction, quantification and characterization of uterine magnetomyographic activity—A proof of concept case study
02 March 2009
Abstract: Objective: The objective was to extract, quantify and characterize the uterine magnetomyographic (MMG) signals that correspond to the electrophysiological activity of the uterus. Methods: Tr...
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Hari Eswaran,
Rathinaswamy B. Govindan,
Adrian Furdea,
Pam Murphy,
Curtis L. Lowery,
Hubert T. Preissl
et al.
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S96-S100
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Effects of the individual uterine contraction on fetal head descent and cervical dilatation during the active stage of labor
02 March 2009
Abstract: Objective: To evaluate the effects of individual uterine contractions on instantaneous values of cervical dilatation and head station along the active stage of labor. Study design: Cervix di...
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Oded Luria,
Ariel Jaffa,
Dan Farine,
Sonia Hassan,
Andrzej Lysikiewicz,
Salim Kees,
Ofer Barnea
et al.
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S101-S107
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| Biomechanics of the placental and umbilical cord |
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Bioengineering aspects of the umbilical cord
02 March 2009
Abstract: The umbilical cord and its constituent tissues: an outer layer of amnion, porous Wharton's jelly, two umbilical arteries, and one umbilical vein, are designed to protect blood flow to the fe...
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Virginia L. Ferguson,
Reuben B. Dodson
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S108-S113
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Imaging of placental transport mechanisms: A review
02 March 2009
Abstract: Functional analysis of material transfers requires precise statement of residence times in each tissue compartment. For the placenta, neither extractive biochemistry, isotope partitioning, n...
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Elisabeth Sölder,
Irena Rohr,
Christian Kremser,
Peter Hutzler,
Paul L. Debbage
et al.
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S114-S120
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| Bioengineering of fetal membranes |
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Biomechanics of the fetal membrane prior to mechanical failure: Review and implications
02 March 2009
Abstract: Annually, premature birth is a major public health problem accounting for over 13,000 deaths and 30,000 surviving infants with life-long morbidity. Preterm premature rupture of the membranes...
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Erinn M. Joyce,
John J. Moore,
Michael S. Sacks
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S121-S127
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Do we know the strength of the chorioamnion? A critical review and analysis
02 March 2009
Abstract: The chorioamnion is the membrane that surrounds the fetus during gestation. Normally, it must remain intact for the duration of pregnancy, 37–42 weeks, and only rupture during or just before...
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Wesley K. Chua,
Michelle L. Oyen
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S128-S133
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Relation between mechanical properties and microstructure of human fetal membranes: An attempt towards a quantitative analysis
02 March 2009
Abstract: Objective: We sought to measure the mechanical baseline behavior of fetal membranes in order to determine constitutive mechanical model parameters for fetal membranes, and to examine their r...
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Mahmood Jabareen,
Ajit Sankar Mallik,
Grozdana Bilic,
Andreas Hugo Zisch,
Edoardo Mazza
et al.
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S134-S141
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Presealing of the chorioamniotic membranes prior to fetoscopic surgery: Preliminary study with unfertilised chicken egg models
02 March 2009
Abstract: Background: Fetoscopic surgical techniques continue to develop. However, progress has been hindered by premature rupture of membranes (PROM), which complicates 5–30% of fetoscopic procedures...
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Helen K. Carnaghan,
Michael R. Harrison
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S142-S145
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| Biomechanics of the pelvic floor |
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Tissue mechanics, animal models, and pelvic organ prolapse: A review
02 March 2009
Abstract: Pelvic floor disorders such as pelvic organ prolapse, urinary incontinence, and fecal incontinence affect a large number of women each year. The pelvic floor can be thought of as a biomechan...
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Steven D. Abramowitch,
Andrew Feola,
Zegbeh Jallah,
Pamela A. Moalli
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S146-S158
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Dynamics of female pelvic floor function using urodynamics, ultrasound and Magnetic Resonance Imaging (MRI)
02 March 2009
Abstract: In this review the diagnostic potential of evaluating female pelvic floor muscle (PFM) function using magnetic and ultrasound imaging in the context of urodynamic observations is considered ...
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Christos E. Constantinou
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S159-S165
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The influence of an occipito-posterior malposition on the biomechanical behavior of the pelvic floor
02 March 2009
Abstract: Objectives: Contribute to the clarification of the mechanisms behind pelvic floor disorders related to a vaginal delivery. Verify the effect of an occipito-posterior malposition of the fetus...
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M.P.L. Parente,
R.M. Natal Jorge,
T. Mascarenhas,
A.A. Fernandes,
J.A.C. Martins
et al.
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S166-S169
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| Uterine hemodynamics |
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The effects of the ovarian cycle and pregnancy on uterine vascular impedance and uterine artery mechanics
05 March 2009
Abstract: Objectives: Uterine vascular resistance (UVR) is the ratio of systemic mean arterial pressure to mean uterine blood flow and is sensitive to changes in small arteries and arterioles. However...
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Benjamin J. Sprague,
Terrance M. Phernetton,
Ronald R. Magness,
Naomi C. Chesler
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S170-S178
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Changes in haemodynamic and autonomous nervous system parameters measured non-invasively throughout normal pregnancy
02 March 2009
Abstract: Objective: To examine non-invasively haemodynamic and autonomous parameters throughout normal pregnancy. Study design: We used the Task Force® Monitor 3040i system to retrieve, record, and c...
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Manfred G. Moertl,
Daniela Ulrich,
Karoline I. Pickel,
Philipp Klaritsch,
Monika Schaffer,
Doris Flotzinger,
Isa Alkan,
Uwe Lang,
Dietmar Schlembach
et al.
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S179-S183
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Transmission line models to simulate the impedance of the uterine vasculature during the ovarian cycle and pregnancy
02 March 2009
Abstract: Objectives: Changes in uterine vascular impedance may yield diagnostic insight into physiological and pathological changes in uterine vascular resistance and compliance during the ovarian cy...
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Yanmei Zhu,
Benjamin J. Sprague,
Terrance M. Phernetton,
Ronald R. Magness,
Naomi C. Chesler
et al.
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S184-S191
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| Sperm transport |
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The role of ultrasound in assessment of male fertility
02 March 2009
Abstract: Ultrasonography (US) is a widely used and well tolerated imaging modality for evaluation of pathologic conditions of the testes. Recent technical advances of US applications and post process...
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Matthias Schurich,
Friedrich Aigner,
Ferdinand Frauscher,
Leo Pallwein
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S192-S198
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Oxidative stress and epididymal sperm transport, motility and morphological defects
02 March 2009
Abstract: Objectives: Radical oxidative species (ROS) have an important effect on sperm quality and quantity. Oxidative stress (OS) occurs when production of potentially destructive reactive oxygen sp...
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Moustafa A.A. El-Taieb,
Ralf Herwig,
Essam A. Nada,
Joachim Greilberger,
Michael Marberger
et al.
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S199-S203
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