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Case report| Volume 95, ISSUE 2, P184-186, April 2001

Severe congenital cytomegalovirus infection with fetal hydrops in a cytomegalovirus-seropositive healthy woman

  • Takuya Inoue
    Correspondence
    Corresponding author. +81-75-751-3281; fax: +81-75-761-3967
    Affiliations
    Department of Gynecology and Obstetrics, Faculty of medicine, Kyoto University, Graduate School of Medicine, Shogoin Kawahara-cho 54, Sakyo-ku, 606-8507 Kyoto, Japan
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  • Noriomi Matsumura
    Affiliations
    Department of Gynecology and Obstetrics, Faculty of medicine, Kyoto University, Graduate School of Medicine, Shogoin Kawahara-cho 54, Sakyo-ku, 606-8507 Kyoto, Japan
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  • Masatsune Fukuoka
    Affiliations
    Department of Gynecology and Obstetrics, Faculty of medicine, Kyoto University, Graduate School of Medicine, Shogoin Kawahara-cho 54, Sakyo-ku, 606-8507 Kyoto, Japan
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  • Norimasa Sagawa
    Affiliations
    Department of Gynecology and Obstetrics, Faculty of medicine, Kyoto University, Graduate School of Medicine, Shogoin Kawahara-cho 54, Sakyo-ku, 606-8507 Kyoto, Japan
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  • Shingo Fujii
    Affiliations
    Department of Gynecology and Obstetrics, Faculty of medicine, Kyoto University, Graduate School of Medicine, Shogoin Kawahara-cho 54, Sakyo-ku, 606-8507 Kyoto, Japan
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      Abstract

      We report the case of a woman whose two consecutive pregnancies resulted in intrauterine fetal death due to severe congenital cytomegalovirus infection. In both pregnancies, congenital cytomegalovirus infection was prenatally diagnosed on the basis of detection of cytomegalovirus DNA and specific IgM in cord blood. This case suggests that severe congenital cytomegalovirus infection can occur even in seropositive healthy women.

      Keywords

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