Abstract
Objective: To determine the endocrinological and clinical outcomes of a 3-day clomiphene citrate
(CC) regimen and compare it with the classical 5-day clomiphene citrate regimen. Study design: 59 patients, diagnosed with Class II ovulatory deficiency according to the criteria
defined by WHO, were randomized into two groups. Patients in Group I received 50 mg per day of CC for 3 days starting on the first day of the cycle during 72 cycles.
Group II received 50 mg per day of CC for 5 days starting on the fifth day during 64 cycles. Result(s): The ovulation rate was significantly higher in Group II (78.11%) compared to Group
I (63.88%) (P<0.05). However, the implantation rate was higher in Group I than Group II. Conclusion: We observed that starting CC on the first day of the cycle for 3 days would lead
to higher implantation rates compared to the classical 5-day CC therapy.
Keywords
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labelled clomiphene citrate.Article info
Publication history
Accepted:
December 22,
2003
Received in revised form:
September 1,
2003
Received:
February 1,
2003
Identification
Copyright
© 2004 Published by Elsevier Inc.
