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Research Article| Volume 159, ISSUE 1, P62-66, November 2011

Maternal morbidity associated with placenta praevia among women who had elective caesarean section

  • Chidimma Onwere
    Affiliations
    Office for Clinical Research and Audit, Royal College of Obstetricians and Gynaecologists, London, UK
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  • Ipek Gurol-Urganci
    Affiliations
    Office for Clinical Research and Audit, Royal College of Obstetricians and Gynaecologists, London, UK

    Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, UK
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  • David A. Cromwell
    Correspondence
    Corresponding author. Department of Health Services Research & Policy, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT Tel.: +44 0 20 78696608; fax: +44 0 20 78696644.
    Affiliations
    Office for Clinical Research and Audit, Royal College of Obstetricians and Gynaecologists, London, UK

    Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, UK
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  • Tahir A. Mahmood
    Affiliations
    Office for Clinical Research and Audit, Royal College of Obstetricians and Gynaecologists, London, UK
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  • Allan Templeton
    Affiliations
    Office for Clinical Research and Audit, Royal College of Obstetricians and Gynaecologists, London, UK
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  • Jan H. van der Meulen
    Affiliations
    Office for Clinical Research and Audit, Royal College of Obstetricians and Gynaecologists, London, UK

    Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, UK
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      Abstract

      Objective

      Estimates of the increased risk of maternal complications after caesarean section posed by placenta praevia differ between studies and may not reflect current practice. We assess the impact of placenta praevia on maternal complications after elective caesarean section (CS).

      Study design

      We undertook a retrospective cohort study of women who had an elective CS for a singleton at term in the English National Health Service between 1 April 2000 and 28 February 2009 using routine data from the Hospital Episode Statistics database. Multiple logistic regression was used to estimate the effect of placenta praevia on maternal complications after controlling for maternal age, parity, whether a woman had a previous CS, and gestational age. Maternal complications included postpartum haemorrhage, obstetric trauma, blood transfusion and hysterectomy.

      Results

      Among 131,731 women having an elective CS for a singleton, 4,332 (3.3%) women had placenta praevia. Placenta praevia increased the risk of postpartum haemorrhage from 9.7% to 17.5% (adjusted odds ratio (OR) 1.91; 95% CI: 1.74 to 2.09), the risk of blood transfusion from 1.4% to 6.4% (OR 4.39; 3.76 to 5.12), and the risk of hysterectomy from 0.03% to 1% (OR 39.70; 22.42 to 70.30). Previous studies have estimated the rate of hysterectomy among women with placenta praevia to be 5%.

      Conclusion

      Placenta praevia remains a risk factor for various maternal complications, although the increased risk of hysterectomy is lower than previously reported.

      Keywords

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