Abstract
Managing women who are pregnant and with a diagnosis of cervical cancer has many complex
challenges. This case report describes the diagnosis and management of a patient presenting
in her first trimester with stage 2B cervical cancer. In conjunction with this a literature
review was undertaken using the following databases from the years 1970–2010: Embase,
CINAHL, Medline and DARE. We examined the number of cases reported in the literature
in which chemotherapy also was used in pregnant women with a cervical malignancy.
Twenty-four papers were retrieved describing in total (including the present case)
35 cases of cervical cancer in pregnancy treated with this modality. Cisplatin therapy
would seem the most reliable form of treatment, permitting a good outcome for most
patients. The effect of delaying radiotherapy to permit pregnancy to fetal viability
in larger tumours cannot be elucidated.
Keywords
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Article info
Publication history
Published online: September 25, 2013
Accepted:
September 11,
2013
Received in revised form:
February 13,
2012
Received:
April 26,
2011
Identification
Copyright
© 2013 Elsevier Ireland Ltd. Published by Elsevier Inc. All rights reserved.