Abstract
The objective of this study was to review management and results of surgical therapy
of intravenous leiomyomatosis (IVL). A retrospective review of five patients treated
at the Mayo Clinic between 2002 and 2012 and a literature review from 1970 to the
present were performed.
IVL is a rare condition, often overlooked, misdiagnosed or inadequately treated. Despite
its benign histological features, invasion of large vessels and cardiac extension
can occur and be fatal. Appropriate diagnosis and a radical surgical approach to IVL
provide optimal outcomes. Incomplete resection and/or microscopic foci of IVL can
lead to recurrence. Surgery should always aim for complete tumor excision and include
hysterectomy and bilateral salpingoophorectomy. Radical parametrectomy and intravenous
tumor resection may be necessary.
Keywords
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Article info
Publication history
Published online: October 14, 2013
Accepted:
September 24,
2013
Received in revised form:
September 5,
2013
Received:
May 2,
2013
Identification
Copyright
© 2013 Elsevier Ireland Ltd. Published by Elsevier Inc. All rights reserved.
