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LETTER TO THE EDITOR – BRIEF COMMUNICATION| Volume 171, ISSUE 2, P390-391, December 2013

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Reproductive outcomes after progestin therapy in infertile women with endometrial atypical hyperplasia

Published:October 16, 2013DOI:https://doi.org/10.1016/j.ejogrb.2013.10.006
      The aim of this study was to investigate the incidence, clinicopathological features, and reproductive outcomes of atypical endometrial hyperplasia (AH) in infertile patients. Endometrial carcinoma (EC) or AH are detected at a higher rate among infertile patients. This elevated incidence of EC may be the result of unopposed estrogen stimulation, e.g. ovulation disorders, progesterone deficiency, or polycystic ovaries. Although the safety and efficacy of fertility-preserving therapies have been demonstrated, there are few publications reporting successful pregnancies after this type of treatment [
      • Kimming R.
      • Strowitzki T.
      • Müller-Höcker J.
      • Kürzl R.
      • Korell M.
      • Hepp H.
      Conservative treatment of endometrial cancer permitting subsequent triplet pregnancy.
      ].
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