Abstract
Past studies have clearly shown the existence of a spectrum of endometrial progesterone
responses in neonatal endometrium, varying from proliferation to full decidualization
with menstrual-like shedding. The bleedings represent, similar to what occurs in adult
menstruation, a progesterone withdrawal bleeding. Today, the bleeding is completely
neglected and considered an uneventful episode of no clinical significance. Yet clinical
studies have linked the risk of bleeding to a series of events indicating fetal distress.
The potential link between the progesterone response and major adolescent disorders
requires to be investigated by prospective studies.
Keywords
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Article info
Publication history
Published online: November 24, 2015
Accepted:
November 17,
2015
Received:
September 3,
2015
Identification
Copyright
© 2015 Elsevier Ireland Ltd. Published by Elsevier Inc. All rights reserved.
