Abstract
Objective
Those patients who failed to achieve continence after a procedure aimed to correct
it, require a special attitude and precise management due to the sophisticated anatomical
and functional field of interest. The purpose of the present study was to assess long-term
clinical efficacy and evaluate the frequency and severity of any complications related
to recurrent stress urinary incontinence treatment with a non-absorbable bulking agent
periurethral injections.
Study design
Between February 2012–September 2013, 66 patients with recurrent stress urinary incontinence
were treated with Urolastic in the tertiary referral gynecologic department. The efficacy
of the procedure was assessed objectively at each follow-up visit, scheduled at two,
six weeks and 3, 6, 12 and 24 months after primary procedure. Material was injected
under local anesthesia according to the manufacturer’s instructions, at 10, 2, 4 and
8 o’clock positions with 0.5–1.25 ccm per spot. Statistical analyses were performed with Statistica package version
8.0 (StatSoft Inc., Tulsa, OK, USA). A p value <0.05 was considered statistically significant.
Results
Objective success rate at 24 months was found in 32.7% of patients, including 22.4%
patients who were completely dry. The efficacy of Urolastic, when considering the
intention to treat, is 24.2% and 16.7%, respectively. In 4.5% patients an oval shaped
material was found inside the bladder. Overall, complications were observed in 17
(25.8%) patients.
Conclusions
Although only 30% of patients will benefit from Urolastic injection on the long-term
basis it seems to be a safe procedure in the treatment of recurrent stress urinary
incontinence.
Keywords
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Article info
Publication history
Published online: October 26, 2016
Accepted:
October 18,
2016
Received in revised form:
September 8,
2016
Received:
May 2,
2016
Identification
Copyright
© 2016 Elsevier Ireland Ltd. All rights reserved.
