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Association between parity and ovarian reserve in reproductive age women

  • Ashraf Moini
    Affiliations
    Department of Gynecology and Obstetrics, Arash Women’s Hospital, Tehran University of Medical Sciences, Resalat Highway, Rashid Avenue, Tehran, Iran

    Department of Endocrinology and Female Infertility at Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran
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  • Manigeh Hedayatshodeh
    Affiliations
    Department of Gynecology and Obstetrics, Arash Women’s Hospital, Tehran University of Medical Sciences, Resalat Highway, Rashid Avenue, Tehran, Iran
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  • Reihaneh Hosseini
    Correspondence
    Corresponding author. Fax: +98 21 77883196.
    Affiliations
    Department of Gynecology and Obstetrics, Arash Women’s Hospital, Tehran University of Medical Sciences, Resalat Highway, Rashid Avenue, Tehran, Iran
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  • Hadith Rastad
    Affiliations
    Research Development Center, Arash Women’s Hospital, Tehran University of Medical Sciences, Resalat Highway, Rashid Avenue, Tehran, Iran
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Published:November 09, 2016DOI:https://doi.org/10.1016/j.ejogrb.2016.10.024

      Abstract

      Objective

      A number of factors affect ovarian reserve. In this study, we investigate the association between parity and ovarian reserve in reproductive age women.

      Materials and methods

      This cross-sectional study was conducted on 186 women aged 20–35 years. The participants were divided into two main groups. Group A (n = 93) included women with at least one parity (pregnancy after 28 weeks), while group B (n = 93) included women with no history of pregnancy. We evaluated the following factors related to ovarian reserve: follicle-stimulating hormone (FSH), ovarian antral follicles, anti-Müllerian hormone (AMH), and ovarian volume.

      Results

      A total of 186 women with a mean age of 27.83 ± 4.49 years enrolled in this study. There was a difference in mean AMH between the nulliparous (2.53 ± 1.90 ng/ml) and multiparous (3.54 ± 1.42 ng/ml) groups (p < 0.001). FSH levels were from 5.27 ± 1.8 mIU/mL in nulliparous women to 5.01 ± 1.9 mIU/mL in multiparous women, which did not significantly differ (p = 0.36). Antral follicles and ovarian size in multiparous women increased significantly (p < 0.001).

      Conclusion

      Parity has a significant association with higher levels of ovarian reserve markers.

      Keywords

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