Abstract
Objective
To evaluate changes in ovarian reserve in patients following hysterectomy, with or
without bilateral salpingectomy or fimbriectomy.
Study design
Open-label, prospective cohort trial of patients undergoing hysterectomy for benign
uterine indications. Levels of follicle-stimulating hormone (FSH), anti-Müllerian
hormone (AMH), and ultrasonic measures of peak systolic flow velocity/diastolic velocity
(S/D) ratio and resistance index (RI) in the ovarian artery were taken from patients
before and 6 weeks after hysterectomy, hysterectomy + salpingectomy or hysterectomy + fimbriectomy.
Results
The study period was from November 2011 to May 2014. Sixty patients were included
in the final analysis, after two patients were lost to follow-up and one patient underwent
bilateral oophorectomy. Of these 60 patients, 16 underwent hysterectomy alone (control
group), and 44 were included in the study group (22 patients underwent hysterectomy + fimbriectomy and 22 patients underwent hysterectomy + salpingectomy). The mean age of patients was 46 years (standard deviation 4.07 years).
Between-group dfferences in FSH, AMH, ovarian volume, ovarian artery S/D ratio and
ovarian artery RI were not significant.
Conclusion
The addition of salpingectomy or fimbriectomy to routine hysterectomy in premenopausal
patients does not diminish ovarian reserve.
Keywords
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Article info
Publication history
Published online: December 26, 2016
Accepted:
December 19,
2016
Received in revised form:
September 26,
2016
Received:
July 14,
2016
Identification
Copyright
© 2016 Elsevier Ireland Ltd. All rights reserved.
