A 35 year-old nulliparous white woman was referred to the Department of Obstetrics and
Gynecology at the University of Bari in July 2007 with a 6 weeks’ history of amenorrhea
and increased level of serum human Chorionic Gonadotropin 125 IU/ml. Transvaginal ultrasound revealed the presence of a 2 × 2 cm right adnexal mass and diagnosis of ectopic pregnancy was placed. HCG level dropped
in the next days to 38 and remained stable for the next two months. Diagnosis of persistent
trophoblastic disease was made and the patient received 3 cycles of metothrexate (1 mg/sqm on day 1-3-5-7 with folinic acid rescue) but h-CG levels remained still stable
(31 UI/ml). Pelvic ultrasound, total body CT scan, MRI of the pelvis, D&C were all negative.
Diagnostic laparoscopy was performed but no pathologic finding was found. Blood samples
revealed nohyperglycosilated hCG which is specific to trophoblastic disease.
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References
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Article info
Publication history
Published online: November 10, 2017
Received:
July 5,
2017
Identification
Copyright
© 2017 Published by Elsevier Ireland Ltd.
