Abstract
Objective
Evaluate patient characteristics that are predictors of treatment response and outcomes
in gestational diabetes
Study design
Retrospective cohort of 265 women with gestational diabetes treated with diet/metformin
and/or insulin in a single centre over 2 years.
Results
Multinomial logistic regression showed that (after adjusting for age and ethnicity)
women who were of normal weight were more likely to be on diet and women who were
obese were more likely to be on metformin or metformin and insulin(p = 0.014). Women who were obese were twice more likely to have labour induced than those
with normal weight. Onset of labour was the only parameter significantly associated
with a treatment modality among the three groups (p < 0.001). There was no difference in the incidence of large for gestational age, neonatal
admission, shoulder dystocia or still birth between the three groups.
Conclusions
Maternal BMI appears to be the only parameter that is predictive of need for treatment
with metformin/insulin and the modality of treatment does not have an effect on maternal
and neonatal outcomes.
Keywords
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Article info
Publication history
Published online: November 20, 2017
Accepted:
November 19,
2017
Received in revised form:
November 18,
2017
Received:
July 1,
2017
Identification
Copyright
© 2017 Elsevier B.V. All rights reserved.
