Up to 70% of American women develop uterine fibroids (benign smooth muscle tumors)
by age 49 [
[1]
]. Myomectomy, surgical removal of fibroids while preserving the uterus, offers a treatment
option for women who desire future fertility [
[1]
]. Although a common gynecologic procedure, myomectomy is not appropriate for patients
with suspected or known cancer. Yet fibroids may present with similar symptoms as
uterine sarcomas, and there is heightened concern about unrecognized uterine cancer
since the U.S. Food and Drug Administration issued safety warnings against power morcellation
of uterine tissues [
[2]
]. However, data on the risk of unexpected uterine cancer specifically for women undergoing
myomectomy are limited, as prior research has centered on hysterectomies (surgical
removal of the uterus). We addressed this important gap using a large population-based
sample.To read this article in full you will need to make a payment
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References
- Management of uterine fibroids. Comparative Effectiveness Review No. 195.Agency for Healthcare Research and Quality, Rockville, MD2017https://doi.org/10.23970/AHRQEPCCER195 (AHRQ Publication No. 17(18)-EHC028-EF. https://effectivehealthcare.ahrq.gov/topics/uterine-fibroids/research-2017)
- FDA updated assessment of the use of laparoscopic power morcellators to treat uterine fibroids.Silver Spring, MD2017 (Available at: https://www.fda.gov/downloads/MedicalDevices/ProductsandMedicalProcedures/SurgeryandLifeSupport/UCM584539.pdf. Accessed August 14, 2018)
- Laparoscopic myomectomy: A single-center retrospective review of 514 patients.J Minim Invasive Gynecol. 2017; 24: 485-493
- Age-stratified risk of unexpected uterine sarcoma following surgery for presumed benign leiomyoma.Oncologist. 2015; 20: 433-439
- Assessing the risk of laparoscopic morcellation of occult uterine sarcomas during hysterectomy and myomectomy: Literature review and the ISGE recommendations.Eur J Obstet Gynecol Reprod Biol. 2018; 220: 30-38
Article info
Publication history
Published online: March 20, 2019
Received:
December 20,
2018
Identification
Copyright
© 2019 Elsevier B.V. All rights reserved.