Abstract
Several studies have investigated the importance of maternal, fetal factors and intrapartum
characteristics in predicting severe perineal lacerations. The purpose of the present
systematic review is to accumulate current evidence and provide estimated effect sizes
for the various risk factors described. We reviewed Medline, Scopus, Clinicaltrials.gov,
EMBASE, Cochrane Central Register of Controlled Trials CENTRAL and Google Scholar
for published studies in the field for observational studies as well as randomized
controlled trials. Two researchers independently assessed the included studies and
documented outcomes. Data extraction was performed using a modified data form that
was based in Cochrane`s data collection form for intervention reviews for RCTs and
non-RCTs. Forty-three articles were selected for inclusion in the present systematic
review. The analyzed population reached 716,031 parturient of whom 22,280 (3,1%) sustained
third- and fourth-degree perineal lacerations. Several risk factors were identified.
Instrumental delivery [RR 3.38 (2.21, 5.18)], midline episiotomy [RR 2.88 (1.79, 4.65)]
and a persistent occiput posterior position [RR 2.73 (2.08, 3.58)] were associated
with the higher risk of developing severe perineal lacerations. Mediolateral episiotomy
did not increase, but was also not protective against perineal lacerations [RR 1.55
(0.95, 2.53)]. Several factors contribute to the development of severe perineal lacerations.
The present meta-analysis presents accumulated data that may help physicians estimate
risks and provide appropriate patient counseling.
Keywords
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References
- Stemming the global caesarean section epidemic.Lancet. 2018; 392: 1279
- WHO statement on caesarean section rates.Bjog Int J Obstet Gynaecol. 2016; 123: 667-670
- FIGO position paper: how to stop the caesarean section epidemic.Lancet. 2018; 392: 1286-1287
- Practice bulletin No. 165: prevention and management of obstetric lacerations at vaginal delivery.Obstet Gynecol. 2016; 128: e1-e15
- The effect of perineal lacerations on pelvic floor function and anatomy at 6 months postpartum in a prospective cohort of nulliparous women.Birth (Berkeley, Calif). 2016; 43: 293-302
- Obstetric anal sphincter injuries at vaginal delivery: a review of recently published national guidelines.Obstet Gynecol Surv. 2018; 73: 695-702
- Risk factors for severe perineal lacerations during childbirth.Int J Gynaecol Obstet. 2014; 125: 6-14
- The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration.J Clin Epidemiol. 2009; 62: e1-34
- Obstetric anal sphincter injury: a systematic review of information available on the internet.Int Urogynecol J. 2019; 30: 713-723
- Epidural analgesia in association with duration of labor and mode of delivery: a quantitative review.Am J Obstet Gynecol. 1999; 180: 970-977
- The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomized studies in meta-analysis.2011www.ohri.ca/programs/clinical_epidemiology/oxford.asp
- Why and how sources of heterogeneity should be investigated.in: Group BP Systematic reviews in health care. BMJ Publishing Group, London2001: 157-175
- Immunotherapy with Sipuleucel-T (APC8015) in patients with metastatic castration-refractory prostate cancer (mCRPC): a systematic review and meta-analysis.Int Braz J Urol. 2012; 38: 717-727
- Closing the gap between methodologists and end-users: R as a computational back-end.J Stat Softw. 2012; 1 (2012)
- Plea for routinely presenting prediction intervals in meta-analysis.BMJ Open. 2016; 6e010247
- Episiotomies and the occurrence of severe perineal lacerations.Br J Obstet Gynaecol. 1994; 101: 1064-1067
- Association between median episiotomy and severe perineal lacerations in primiparous women.CMAJ. 1997; 156: 797-802
- Determinants of vaginal-perineal integrity and pelvic floor functioning in childbirth.Am J Obstet Gynecol. 1997; 176: 403-410
- Episiotomy, operative vaginal delivery, and significant perinatal trauma in nulliparous women.Am J Obstet Gynecol. 1999; 181: 1180-1184
- Incidence and risk factors for third degree perineal tears.Int J Gynaecol Obstet. 2000; 71: 227-229
- Anal sphincter tears: prospective study of obstetric risk factors.BJOG. 2000; 107: 926-931
- Severe perineal lacerations during vaginal delivery: the University of Miami experience.Am J Obstet Gynecol. 2000; 182: 1083-1085
- Risk factors for third degree perineal ruptures during delivery.BJOG. 2001; 108: 383-387
- Third and fourth degree perineal tears. Predictor factors in a referral hospital.Acta Obstet Gynecol Scand. 2001; 80: 229-234
- Risk factors for third-degree perineal tears in vaginal delivery, with an analysis of episiotomy types.J Reprod Med. 2001; 46: 752-756
- Risk factors for severe perineal tear: can we do better?.Am J Perinatol. 2002; 19: 225-234
- Incidence, severity, and determinants of perineal pain after vaginal delivery: a prospective cohort study.Am J Obstet Gynecol. 2004; 191: 1199-1204
- Does the angle of episiotomy affect the incidence of anal sphincter injury?.BJOG. 2006; 113: 190-194
- Factors predicting severe perineal trauma during childbirth: role of forceps delivery routinely combined with mediolateral episiotomy.Am J Obstet Gynecol. 2005; 192: 875-881
- Third degree perineal tears in a university medical center where midline episiotomies are not performed.Arch Gynecol Obstet. 2005; 271: 307-310
- The role of mediolateral episiotomy during labour: analysis of risk factors for obstetric anal sphincter tears.Acta Obstet Gynecol Scand. 2006; 85: 856-860
- An Australian prospective cohort study of risk factors for severe perineal trauma during childbirth.Midwifery. 2007; 23: 196-203
- Risk factors for primary and subsequent anal sphincter lacerations: a comparison of cohorts by parity and prior mode of delivery.Am J Obstet Gynecol. 2007; 196: e1-5
- Operative vaginal delivery and midline episiotomy: a bad combination for the perineum.Am J Obstet Gynecol. 2006; 195: 749-754
- Advanced age is a risk factor for higher grade perineal lacerations during delivery in nulliparous women.Arch Gynecol Obstet. 2010; 281: 59-64
- Risk factors for severe perineal injury during childbirth: a case-control study of 60 consecutive cases.Colorectal Dis. 2011; 13: e216-9
- Third- and fourth-degree perineal tears: prevalence and risk factors in the third millennium.Am J Obstet Gynecol. 2011; 204: e1-4
- Risk factors for severe perineal trauma during vaginal childbirth: a Western Australian retrospective cohort study.Women Birth. 2015; 28: 16-20
- Identification of women at high risk for severe perineal lacerations.Eur J Obstet Gynecol Reprod Biol. 2014; 182: 11-15
- Severe perineal laceration during operative vaginal delivery: the impact of occiput posterior position.J Perinatol. 2014; 34: 898-900
- Prevalence and contributing factors of severe perineal damage following episiotomy-assisted vaginal delivery.Taiwan J Obstet Gynecol. 2014; 53: 481-485
- The impact of first birth obstetric anal sphincter injury on the subsequent birth: a population-based linkage study.BMC Pregnancy Childbirth. 2015; 15: 31
- Shoulder dystocia and associated manoeuvres as risk factors for perineal trauma.Int Urogynecol J. 2016; 27: 571-577
- Risk factors for severe obstetric perineal lacerations.Int Urogynecol J. 2016; 27: 61-67
- Obesity may Be protective against severe perineal lacerations.J Obes. 2016; (2016)9376592
- Simulation training for forceps-assisted vaginal delivery and rates of maternal perineal trauma.Obstet Gynecol. 2016; 128: 429-435
- Episiotomy and the risk of severe perineal injuries among Korean women.J Matern Neonatal Med. 2017; 30: 1745-1749
- Incidence and risk factors of third- and fourth-degree perineal tears in a single Italian scenario.Eur J Obstet Gynecol Reprod Biol. 2018; 221: 139-143
- Risk factors for obstetric anal sphincter injuries (OASI) at a tertiary centre in south India.Int Urogynecol J. 2018; 29: 391-396
- Third and fourth degree perineal tear in four-year period at sestre milosrdnice university hospital center, Zagreb, Croatia.Open Access Maced J Med Sci. 2018; 6: 1067-1071
- Risk factors for obstetric anal sphincter injuries (OASIS) during vacuum extraction delivery in a university affiliated maternity hospital.J. Maternal-Fetal Neonatal Med. 2018; : 1-5
- Risk factors for poor perineal outcome after operative vaginal delivery.J Perinatol. 2018; 38: 1625-1630
- Factors associated with obstetric anal sphincter injuries in midwife-led birth: a cross sectional study.Midwifery. 2018; 62: 264-272
- Incidence and risk factors of severe lacerations during forceps delivery in a single teaching hospital where simulation training is held annually.J Obstet Gynaecol Res. 2018; 44: 708-716
- Risk factors for the development of obstetric anal sphincter injuries in modern obstetric practice.Obstet Gynecol. 2018; 131: 290-296
- Risk factors for perineal trauma in the primiparous population during non-operative vaginal delivery.Int Urogynecol J. 2019;
- Obstetric perineal tears: risk factors, wound infection and dehiscence: a prospective cohort study.Arch Gynecol Obstet. 2019; 300: 67-77
- Factors associated with obstetric anal sphincter injuries during vacuum delivery among Chinese women.Int J Gynaecol Obstet. 2019; 145: 354-360
- Methods of classification for women undergoing induction of labour: a systematic review and novel classification system.Bjog Int J Obstet Gynaecol. 2015; 122: 1284-1293
- Changing incidence of obstetric anal sphincter injuries-A result of formal prevention programs?.Acta Obstet Gynecol Scand. 2019; 98: 1455-1463
- Fuzzy logic and neural networks.IEEE Trans Neural Netw. 1992; 3: 636-639
Article info
Publication history
Published online: February 14, 2020
Accepted:
February 13,
2020
Received in revised form:
February 11,
2020
Received:
January 6,
2020
Identification
Copyright
© 2020 Elsevier B.V. All rights reserved.