Abstract
Objectives
The relationship between pelvic organ prolapse (POP) treatment and subjective pelvic-floor
related quality of life (QoL) was examined.
Study design
130 postmenopausal women with symptomatic POP were included: 45 % (59/130) were treated
conservatively with pessary and 55 % (71/130) underwent pelvic floor surgery. All
participants answered the validated German pelvic floor questionnaire at the time
of baseline examination, as well as three months later.
Results
Our results demonstrated a significant improvement regarding mean score in the domains
“prolapse” (p = 0.001) and “sexual function” (p = 0.001) three months after prolapse
surgery, whereas in the pessary group only the score in the “prolapse” domain improved
(p < 0.001). When comparing the two treatment arms after three months, patients reported
a significant advancement regarding their “sexual function” domain in the surgery
group (p < 0.0001). Furthermore, univariate analysis revealed a significant positive
correlation between “prolapse” domain score (correlation coefficient = 0.0001) as
well as “bladder” domain score (correlation coefficient <0.001) and POP-Q stage. Additionally,
a significant negative correlation between “sexual function” domain score and POP-Q
stage was found (correlation coefficient = 0.0001).
Conclusion
Our results revealed that three months after prolapse surgery, pelvic-floor related
QoL showed significant improvement in the domain “sexual function” compared to three
months pessary treatment. Besides, advanced prolapse stage correlated with higher
symptom burden and worse sexual function.
Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to European Journal of Obstetrics and Gynecology and Reproductive BiologyAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Risk factors for pelvic organ prolapse and its recurrence: a systematic review.Int Urogynecol J. 2015; 26: 1559-1573https://doi.org/10.1007/s00192-015-2695-8
- Prediction model and prognostic index to estimate clinically relevant Pelvic Organ Prolapse ina general female population.Int Urogynecol J Pelvic. 2009; ([Internet]): 1013-1021
- Pelvic organ prolapse.Lancet. 2007; 369: 1027-1038https://doi.org/10.1016/S0140-6736(07)60462-0
- Symptoms, bother and POPQ in women referred with pelvic organ prolapse.Int Urogynecol J. 2003; 14: 122-127https://doi.org/10.1007/s00192-002-1024-1
- Correlation of symptoms with location and severity of pelvic organ prolapse.Am J Obstet Gynecol. 2001; 185: 1332-1338https://doi.org/10.1067/mob.2001.119078
- The effects of severe cystocele on urogynecologic symptoms and findings.Acta Obstetricia et Gynecologica Scandinavica. 2001; 80: 423-427https://doi.org/10.1080/j.1600-0412.2001.080005423.x
- Pelvic floor dysfunction and its effect on quality of sexual life.Sex Med Rev. 2019; 7: 559-564https://doi.org/10.1016/j.sxmr.2019.05.007
- Predicting treatment choice for patients with pelvic organ prolapse.Obstet Gynecol. 2003; 101: 1279-1284https://doi.org/10.1016/S0029-7844(03)00359-4
- Surgery for women with apical vaginal prolapse.Cochrane Database Syst Rev. 2016; 2016https://doi.org/10.1002/14651858.CD012376
- Surgery for women with posterior compartment prolapse.Cochrane Database Syst Rev. 2018; https://doi.org/10.1002/14651858.CD012975
- Epidemiology of surgically managed pelvic organ prolapse and urinary incontinence.Obstet Gynecol. 1997; 89: 501-506https://doi.org/10.1016/S0029-7844(97)00058-6
- The standardization of terminology of female pelvic organ prolapse and pelvic floor dysfunction.Am J Obstet Gynecol. 1996; 175: 10-17https://doi.org/10.1016/S0002-9378(96)70243-0
- Patient reported and anatomical outcomes after surgery for pelvic organ prolapse.Neurourol Urodyn. 2009; 28: 219-224https://doi.org/10.1002/nau.20626
- How accurate is symptomatic and clinical evaluation of prolapse prior to surgical repair?.Int Urogynecol J Pelvic Floor Dysfunct. 2007; 18: 1179-1183
- P-QOL: a validated questionnaire to assess the symptoms and quality of life of women with urogenital prolapse.Int Urogynecol J. 2005; 16: 176-181https://doi.org/10.1007/s00192-004-1225-x
- Short forms of two condition-specific quality-of-life questionnaires for women with pelvic floor disorders (PFDI-20 and PFIQ-7).Am J Obstet Gynecol. 2005; 193: 103-113https://doi.org/10.1016/j.ajog.2004.12.025
- Further validation of the short form versions of the Pelvic Floor Distress Inventory (PFDI) and Pelvic Floor Impact Questionnaire (PFIQ).Neurourol Urodyn. 2011; 30: 541-546https://doi.org/10.1002/nau.20934
- Relationship between the Pelvic Organ Prolapse Quantification system (POP-Q), the Pelvic Floor Impact Questionnaire (PFIQ-7), and the Pelvic Floor Distress Inventory (PFDI-20) before and after anterior vaginal wall prolapse surgery.Int Urogynecol J. 2015; 26: 195-200https://doi.org/10.1007/s00192-014-2434-6
- Validation of a Pelvic Floor Questionnaire with improvement and satisfaction scales to assess symptom severity, bothersomeness and quality of life before and after pelvic floor therapy.Aktuelle Urol. 2011; 42: 316-322https://doi.org/10.1055/s-0031-1271544
- The standardisation of terminology in lower urinary tract function: report from the standardisation sub-committee of the International Continence Society.Urology. 2003; 61: 37-49https://doi.org/10.1016/S0090-4295(02)02243-4
- Pelvic floor dysfunction.University of Bradford, UK1996
- The POP-Q system: two decades of progress and debate.Int Urogynecol J. 2014; 25: 441-443https://doi.org/10.1007/s00192-013-2262-0
- Stress urinary incontinence and endogenous sex steroids in postmenopausal women.Neurourol Urodyn. 2017; 36: 121-125https://doi.org/10.1002/nau.22885
- Sexuality in German urogynecological patients and healthy controls: is there a difference with respect to the diagnosis?.Eur J Obstet Gynecol Reprod Biol. 2013; 170: 567-570https://doi.org/10.1016/j.ejogrb.2013.08.002
- Symptomatic pelvic organ prolapse at midlife, quality of life, and risk factors.Obstet Gynecol. 2009; : 113
- Quality of life and sexuality after bilateral sacrospinous fixation with vaginal hysterectomy for treatment of primary pelvic organ prolapse.LUTS: Lower Urinary Tract Symptoms. 2020; (n/a)https://doi.org/10.1111/luts.12303
- Body image perceptions in women with pelvic organ prolapse: a qualitative study.Am J Obstet Gynecol. 2011; 204: e1-e5https://doi.org/10.1016/j.ajog.2010.12.024
- Pelvic organ prolapse: a disease of silence and shame.Female Pelvic Med Reconstr Surg. 2014; : 20
- Responsiveness of the Pelvic Floor Distress Inventory (PFDI) and Pelvic Floor Impact Questionnaire (PFIQ) in women undergoing vaginal surgery and pessary treatment for pelvic organ prolapse.Am J Obstet Gynecol. 2006; 194: 1492-1498https://doi.org/10.1016/j.ajog.2006.01.076
- Effect of uterosacral ligament suspension vs sacrospinous ligament fixation with or without perioperative behavioral therapy for pelvic organ vaginal prolapse on surgical outcomes and prolapse symptoms at 5 years in the OPTIMAL randomized clinical trial.JAMA. 2018; 319: 1554-1565https://doi.org/10.1001/jama.2018.2827
- Mesh surgery for anterior vaginal wall prolapse: a meta-analysis.Rev Bras Ginecol Obstet. 2016; 38: 356-364https://doi.org/10.1055/s-0036-1585074
- A 3–year follow-up after anterior colporrhaphy compared with collagen-coated transvaginal mesh for anterior vaginal wall prolapse: a randomised controlled trial.BJOG: Int J Obstet Gynaecol. 2016; 123: 136-142https://doi.org/10.1111/1471-0528.13628
- Changes in the symptoms and quality of life of women with symptomatic pelvic organ prolapse fitted with a ring with support pessary.Maturitas. 2018; 117: 51-56https://doi.org/10.1016/j.maturitas.2018.09.003
- Quality of life and vaginal symptoms of postmenopausal women using pessary for pelvic organ prolapse: a prospective study.Revista Da Associação Médica Brasileira. 2018; 64: 1103-1107
- Prospective evaluation of outcome of vaginal pessaries versus surgery in women with symptomatic pelvic organ prolapse.Int Urogynecol J. 2011; 22: 273-278https://doi.org/10.1007/s00192-010-1340-9
- One-year prospective comparison of vaginal pessaries and surgery for pelvic organ prolapse using the validated ICIQ-VS and ICIQ-UI (SF) questionnaires.Int Urogynecol J. 2015; 26: 1305-1312https://doi.org/10.1007/s00192-015-2686-9
- Prevalence and trends of symptomatic pelvic floor disorders in U.S. women.Obstet Gynecol. 2014; 123: 141-148https://doi.org/10.1097/AOG.0000000000000057
- The demographics of pelvic floor disorders: current observations and future projections.Am J Obstet Gynecol. 2001; 184: 1496-1503https://doi.org/10.1067/mob.2001.114868
Article info
Publication history
Published online: February 23, 2021
Accepted:
February 18,
2021
Received in revised form:
January 29,
2021
Received:
September 16,
2020
Identification
Copyright
© 2021 Elsevier B.V. All rights reserved.