Cleft lip and palate (CLP) is on the list of the most prevalent birth defects, with an incidence of 1/700–1000 newborns although variable among populations [
]. Affected individuals experience severe feeding, hearing, speech and psychological problems. Most of CLP cases are supposed to be non-syndromic, presenting with isolated entities and no other congenital anomalies. We here report a Chinese woman in whom a mosaic CDH1 variant was revealed by molecular testing of her offsprings with CLP.
- Rahimov F.
- Jugessur A.
- Murray J.C.
Cleft Palate Craniofac J. 2012; 49: 73-91
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- Cleft Palate Craniofac J. 2012; 49: 73-91
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Published online: September 17, 2021
Accepted: September 13, 2021
Received: August 8, 2021
© 2021 Elsevier B.V. All rights reserved.