To characterize the association between antepartum marijuana exposure and maternal and neonatal outcomes at our institution.
Retrospective chart review identified an obstetric cohort of singleton gestations. Women with self-reported marijuana use were compared with non-users. Demographic characteristics, risk factors, and maternal-fetal outcomes were evaluated. Associations between outcomes and marijuana use were assessed with regression analysis.
Of 2792 deliveries, 5.4% reported marijuana use. Compared to non-users, marijuana users entered prenatal care later, were younger, non-Hispanic, and used other illicit substances. Marijuana users had a higher rate of cesarean delivery (p = 0.01). After adjusting for confounders, marijuana use remained associated with 4.1-fold risk of delivering a small for gestational age (SGA) infant and 2.89-fold risk of neonatal oxygen use.
At a safety net hospital, antepartum marijuana use is significantly associated with cesarean delivery, SGA and supplemental oxygen use at birth. Healthcare disparities associated with marijuana use make this a population of critical interest.
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Published online: September 15, 2021
Accepted: September 13, 2021
Received in revised form: August 31, 2021
Received: May 11, 2021
☆Previously accepted at: ACOG Annual Clinical and Scientific Meeting. April 2020. Seattle, Washington.
© 2021 Published by Elsevier B.V.