Objective: Stressful experiences against the backdrop of perinatal losses (PL) may adversely
affect the course of the next pregnancy, promote fetal distress. The structure of
causes of perinatal mortality fetal distress is one of the leading places. The aim
of the study was to evaluate the possibility cardiointervalography in predicting fetal
distress during perinatal history mother. Study design: A study of heart rate variability by cardiointervalography women with PL associated
with placenta dysfunction in 16-18 weeks of pregnancy by fetal monitor “Kardiolab
Baby Card” (Kharkiv, Ukraine). The study involved 200 pregnant women with PL in the
anamnesis (study group) and 100 pregnant women without PL (control group). For assessment
of adaptive responses using the parameter activity of regulatory systems (PARS), the
calculation is done automatically. Results: Normal adaptive state (PARS = 1-3 points) observed only in 10.0% of pregnant with
PL and in the vast majority (61.0%) patients control group (p <0.05), expressed tension
of regulatory systems was observed in half pregnant study group against 15.0% of women
in the control group (p <0.05). In 22.0% of pregnant women with PL PARS score was
8-10 points, characterized by a failure of adaptation? in the control group similar
condition seen in only 3.0% of women (p<0.05). 48 (24.0%) women of the main group
diagnosed fetal distress (according to Doppler and cardiotocography): 20 (41.7%) of
them - failure of adaptation (PARS = 8-10), while in the absence of fetal distress
failure of adaptation found only in 24 (15.8%), i.e. 8-10 points while in the absence
of fetal distress failure of adaptation found only in value may be a marker of fetal
distress (OR = 3.810 95% CI 1.853-7.832). Conclusions: Evaluation of regulation of the autonomic nervous system in heart rate variability
to evaluate adaptation abilities of women and their use as prognostic markers of fetal
suffering.
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