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81 Possibilities of the cardiointervalography in the forecasted fetal distress at perinatal losses in anamnesis of mather

      Objective: Stressful experiences against the backdrop of perinatal losses (PL) may adversely affect the course of the next pregnancy, promote fetal distress. The structure of causes of perinatal mortality fetal distress is one of the leading places. The aim of the study was to evaluate the possibility cardiointervalography in predicting fetal distress during perinatal history mother. Study design: A study of heart rate variability by cardiointervalography women with PL associated with placenta dysfunction in 16-18 weeks of pregnancy by fetal monitor “Kardiolab Baby Card” (Kharkiv, Ukraine). The study involved 200 pregnant women with PL in the anamnesis (study group) and 100 pregnant women without PL (control group). For assessment of adaptive responses using the parameter activity of regulatory systems (PARS), the calculation is done automatically. Results: Normal adaptive state (PARS = 1-3 points) observed only in 10.0% of pregnant with PL and in the vast majority (61.0%) patients control group (p <0.05), expressed tension of regulatory systems was observed in half pregnant study group against 15.0% of women in the control group (p <0.05). In 22.0% of pregnant women with PL PARS score was 8-10 points, characterized by a failure of adaptation? in the control group similar condition seen in only 3.0% of women (p<0.05). 48 (24.0%) women of the main group diagnosed fetal distress (according to Doppler and cardiotocography): 20 (41.7%) of them - failure of adaptation (PARS = 8-10), while in the absence of fetal distress failure of adaptation found only in 24 (15.8%), i.e. 8-10 points while in the absence of fetal distress failure of adaptation found only in value may be a marker of fetal distress (OR = 3.810 95% CI 1.853-7.832). Conclusions: Evaluation of regulation of the autonomic nervous system in heart rate variability to evaluate adaptation abilities of women and their use as prognostic markers of fetal suffering.
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