Abstract
Objective
The purpose of this study is to analyze the precise anatomical characteristics of
a large group of patients with Herlyn-Werner-Wunderlich syndrome together with the
long-term follow-up and the reproductive performance.
Study design
Retrospective analysis of prospectively collected data. In two tertiary medical centers,
from 2008 to 2021, 51 patients with HWWS underwent surgery via the same technique.
Presenting symptoms, preoperative investigations, operative management, and long-term
follow-up with obstetric outcome were assessed.
Results
The surgical procedure was successful in all cases with no major complications recorded.
Postoperative course was uneventful. The median follow-up was 6,5 years, with a range
from 6 months to 13 years. After surgery, among 14 patients who sought pregnancies,
12 (85,71%) were successful. Of these 11 patients had a total of 22 pregnancies, resulting
in spontaneous miscarriage in 27% (6/22), premature birth (<37 weeks) in 36% (8/22)
and full-term birth in 36% (8/22). Overall the pregnancies demonstrated had a good
course.
Conclusions
Early diagnosis is essential in establishing prompt and correct surgical treatment.
Keywords
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Article info
Publication history
Published online: June 14, 2022
Accepted:
June 12,
2022
Received in revised form:
May 4,
2022
Received:
November 18,
2021
Identification
Copyright
© 2022 Elsevier B.V. All rights reserved.
