Advertisement
Research Article| Volume 282, P38-42, March 2023

Gynaecological pathologies leading to emergency department admissions: A cross-sectional study

  • Anjeza Xholli
    Correspondence
    Corresponding author at: IRCCS Ospedale Policlinico San Martino, Academic Unit of Obstetrics and Gynaecology, Largo Rosanna Benzi, 10, 16132 Genova, Italy.
    Affiliations
    Academic Unit of Obstetrics and Gynaecology, IRCCS Ospedale San Martino, Genoa, Italy

    Department of Neurology, Rehabilitation, Ophthalmology, Genetics, Maternal and Infant Health, University of Genoa, Genoa, Italy
    Search for articles by this author
  • Ambrogio Pietro Londero
    Affiliations
    Department of Neurology, Rehabilitation, Ophthalmology, Genetics, Maternal and Infant Health, University of Genoa, Genoa, Italy
    Search for articles by this author
  • Ludovica Camacho Mattos
    Affiliations
    Nuovo ospedale civile di Sassuolo, Sassuolo, Italy
    Search for articles by this author
  • Sonja Vujosevic
    Affiliations
    Department of Obstetrics and Gynaecology, Gynaecologic Oncology and Minimally-Invasive Pelvic Surgery, IRCCS Sacro Cuore Don Calabria Hospital, Negrar di Valpolicella, Verona, Italy
    Search for articles by this author
  • Angelo Cagnacci
    Affiliations
    Academic Unit of Obstetrics and Gynaecology, IRCCS Ospedale San Martino, Genoa, Italy

    Department of Neurology, Rehabilitation, Ophthalmology, Genetics, Maternal and Infant Health, University of Genoa, Genoa, Italy
    Search for articles by this author
Published:January 06, 2023DOI:https://doi.org/10.1016/j.ejogrb.2023.01.006

      Abstract

      Objective

      Knowing the population’s needs in order to plan measures to reduce emergency department (ED) use is fundamental. The objective of this study was to describe gynaecological ED visits and associated findings in women of reproductive age.

      Methods

      This study was a retrospective anonymized chart review analysis of visits to the ED for gynaecological disturbances at the University Hospital of Modena. All consecutive women of reproductive age were included. Women aged <18 years and postmenopausal women were excluded from this study.

      Results

      In total, 461 records were analysed. The median age was 41 (interquartile range 34–46) years. The most common symptom was dysmenorrhoea (42.7 %), followed by heavy menstrual bleeding (33.2 %). The most common gynaecological findings in the ED were adenomyosis (86.1 %), endometriosis (37.1 %) and leiomyomas (13.7 %). Adenomyosis was the most common finding, regardless of age. Endometriosis was more prevalent in women aged <41 years (43.8 % vs 31.2 %; p < 0.05). Meanwhile, adenomyosis and leiomyomas were more prevalent in women aged ≥41 years (81.11 % vs 90.57 % and 7.37 % vs 19.26 %, respectively; p < 0.05). Moreover, potentially life-threatening findings had low prevalence [i.e. haemorrhagic ovarian cyst (0.2 %), tubo-ovarian abscess (0.2 %) and pelvic inflammatory disease (0.4 %)].

      Conclusion

      In the study setting, chronic pathologies such as adenomyosis, endometriosis and leiomyomas significantly impacted use of the ED. Adenomyosis was the most common pathology, regardless of age. Adenomyosis and leiomyomas were more prevalent in women aged ≥41 years, and endometriosis was more prevalent in women aged <41 years.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      References

        • Kelly E.A.
        • Keller C.C.
        • Sax M.R.
        • Rossi R.A.
        Emergency department utilization of case-managed patients following benign gynecologic surgery.
        Int J Emerg Med. 2020; 13
        • Weinick R.M.
        • Burns R.M.
        • Mehrotra A.
        Many emergency department visits could be managed at urgent care centers and retail clinics.
        Health Aff. 2010; 29: 1630-1636
        • Ho V.
        • Metcalfe L.
        • Dark C.
        • Vu L.
        • Weber E.
        • Shelton G.
        • et al.
        Comparing utilization and costs of care in freestanding emergency departments, hospital emergency departments, and urgent care centers.
        Ann Emerg Med. 2017; 70: 846-857.e3
        • Grandi G.
        • De Fata R.
        • Varliero F.
        • Del Savio M.C.
        • Facchinetti F.
        Contemporary prescriptions pattern of different dose levonorgestrel-releasing intrauterine systems in an Italian service for family planning.
        Gynecol Endocrinol. 2020; 36: 1086-1089
        • Van den Bosch T.
        • Dueholm M.
        • Leone F.P.G.
        • Valentin L.
        • Rasmussen C.K.
        • Votino A.
        • et al.
        Terms, definitions and measurements to describe sonographic features of myometrium and uterine masses: a consensus opinion from the Morphological Uterus Sonographic Assessment (MUSA) Group.
        Ultrasound Obstet Gynecol. 2015; 46: 284-298
        • Munro M.G.
        Classification and reporting systems for adenomyosis.
        J Minim Invasive Gynecol. 2020; 27: 296-308
        • Tellum T.
        • Munro M.G.
        Classifications of adenomyosis and correlation of phenotypes in imaging and histopathology to clinical outcomes: a review.
        Curr Obstet Gynecol Rep. 2022; 11: 1-11
        • Xholli A.
        • Filip G.
        • Previtera F.
        • Cagnacci A.
        Modification of endometrioma size during hormone therapy containing dienogest.
        Gynecol Endocrinol. 2020; 36: 545-549
        • Naftalin J.
        • Hoo W.
        • Pateman K.
        • Mavrelos D.
        • Holland T.
        • Jurkovic D.
        How common is adenomyosis? A prospective study of prevalence using transvaginal ultrasound in a gynaecology clinic.
        Hum Reprod. 2012; 27: 3432-3439
        • Guerriero S.
        • Condous G.
        • van den Bosch T.
        • Valentin L.
        • Leone F.P.G.
        • Van Schoubroeck D.
        • et al.
        Systematic approach to sonographic evaluation of the pelvis in women with suspected endometriosis, including terms, definitions and measurements: a consensus opinion from the International Deep Endometriosis Analysis (IDEA) Group.
        Ultrasound Obstet Gynecol. 2016; 48: 318-332
        • Timmerman D.
        • Valentin L.
        • Bourne T.H.
        • Collins W.P.
        • Verrelst H.
        • Vergote I.
        Terms, definitions and measurements to describe the sonographic features of adnexal tumors: a consensus opinion from the International Ovarian Tumor Analysis (IOTA) Group.
        Ultrasound Obstet Gynecol. 2000; 16: 500-505
        • Belsey E.M.
        • Machines D.
        • d'Arcangues C.
        The analysis of vaginal bleeding patterns induced by fertility regulating methods. World Health Organization Special Programme of Research, Development and Research Training in Human Reproduction.
        Contraception. 1986; 34: 253-260
        • Wyatt K.M.
        • Dimmock P.W.
        • Walker T.J.
        • O’Brien P.M.S.
        Determination of total menstrual blood loss.
        Fertil Steril. 2001; 76: 125-131
        • Xholli A.
        • Simoncini G.
        • Vujosevic S.
        • Trombetta G.
        • Chiodini A.
        • Ferraro M.F.
        • et al.
        Menstrual pain and elasticity of uterine cervix.
        J Clin Med. 2021; 10: 1110
        • Grandi G.
        • Ferrari S.
        • Xholli A.
        • et al.
        Prevalence of menstrual pain in young women: what is dysmenorrhea?.
        J Pain Res. 2012; 5: 169-174
        • Haylen B.T.
        • de Ridder D.
        • Freeman R.M.
        • Swift S.E.
        • Berghmans B.
        • Lee J.
        • et al.
        An International Urogynecological Association (IUGA)/International Continence Society (ICS) joint report on the terminology for female pelvic floor dysfunction.
        Neurourol Urodyn. 2010; 29: 4-20
        • Bertozzi S.
        • Londero A.P.
        • Fruscalzo A.
        • Driul L.
        • Marchesoni D.
        Prevalence and risk factors for dyspareunia and unsatisfying sexual relationships in a cohort of primiparous and secondiparous women after 12 months postpartum.
        Int J Sex Health. 2010; 22: 47-53
      1. Chow S.C. Shao J. Wang H. Sample size calculations in clinical research. 2nd ed. Chapman & Hall/CRC, Boca Raton2008
        • R Core Team
        R: a language and environment for statistical computing.
        R Foundation for Statistical Computing, Vienna2020
        • Yu O.
        • Schulze-Rath R.
        • Grafton J.
        • Hansen K.
        • Scholes D.
        • Reed S.D.
        Adenomyosis incidence, prevalence and treatment: United States population-based study 2006–2015.
        Am J Obstet Gynecol. 2020; 223: 94.e1-94.e10
        • Weiss G.
        • Maseelall P.
        • Schott L.L.
        • Brockwell S.E.
        • Schocken M.
        • Johnston J.M.
        Adenomyosis a variant, not a disease? Evidence from hysterectomized menopausal women in the Study of Women’s Health Across the Nation (SWAN).
        Fertil Steril. 2009; 91: 201-206
        • Filip G.
        • Balzano A.
        • Cagnacci A.
        Histological evaluation of the prevalence of adenomyosis, myomas and of their concomitance.
        Minerv Ginecol. 2019; 71: 177-181
        • Fuldeore M.
        • Yang H.
        • Soliman A.M.
        • Winkel C.
        Healthcare utilization and costs among women diagnosed with uterine fibroids: a longitudinal evaluation for 5 years pre- and post-diagnosis.
        Curr Med Res Opin. 2015; 31: 1719-1731
        • Hartmann K.E.
        • Birnbaum H.
        • Ben-Hamadi R.
        • Wu E.Q.
        • Farrell M.H.
        • Spalding J.
        • et al.
        Annual costs associated with diagnosis of uterine leiomyomata.
        Obstet Gynecol. 2006; 108: 930-937
        • Cardozo E.R.
        • Clark A.D.
        • Banks N.K.
        • Henne M.B.
        • Stegmann B.J.
        • Segars J.H.
        The estimated annual cost of uterine leiomyomata in the United States.
        Am J Obstet Gynecol. 2012; 206: 211.e1-211.e9
        • Fortin C.N.
        • Jiang C.
        • Caldwell M.T.
        • As-Sanie S.
        • Dalton V.
        • Marsh E.E.
        Trends in emergency department utilization among women with leiomyomas in the United States.
        Obstet Gynecol. 2021; 137: 897-905
        • Fuldeore M.
        • Yang H.
        • Du E.X.
        • et al.
        Healthcare utilization and costs in women diagnosed with endometriosis before and after diagnosis: a longitudinal analysis of claims databases.
        Fertil Steril. 2015; 103: 163-171
        • Members of the Endometriosis Guideline Core Group
        • Becker C.M.
        • Bokor A.
        • et al.
        ESHRE Guideline: endometriosis.
        Hum Reprod Open. 2022; 2022: hoac009
        • Ballard K.D.
        • Seaman H.E.
        • de Vries C.S.
        • Wright J.T.
        Can symptomatology help in the diagnosis of endometriosis? Findings from a national case–control study – Part 1.
        BJOG. 2008; 115: 1382-1391
      2. Morassutto C, Monasta L, Ricci G, et al. Incidence and estimated prevalence of endometriosis and adenomyosis in Northeast Italy: a data linkage study. PLoS One 2016;11:e0154227.

        • Balasch J.
        • Creus M.
        • Fabregues F.
        • Carmona F.
        • Ordi J.
        • Martinez-Roman S.
        • et al.
        Visible and non-visible endometriosis at laparoscopy in fertile and infertile women and in patients with chronic pelvic pain: a prospective study.
        Hum Reprod. 1996; 11: 387-391
        • Laufer M.R.
        Current approaches to optimizing the treatment of endometriosis in adolescents.
        Gynecol Obstet Invest. 2008; 66: 19-27
        • Falcone T.
        • Lebovic D.I.
        Clinical management of endometriosis.
        Obstet Gynecol. 2011; 118: 691-705
        • Savelli L.
        Transvaginal sonography for the assessment of ovarian and pelvic endometriosis: how deep is our understanding?.
        Ultrasound Obstet Gynecol. 2009; 33: 497-501