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Are troponin T levels in women with pre-eclampsia related to development of pulmonary oedema?

  • Wing H. Tong
    Affiliations
    Department of Obstetrics and Gynaecology, Division of Obstetrics and Prenatal Medicine, Erasmus MC, University Medical Center Rotterdam, The Netherlands
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  • Author Footnotes
    † Deceased.
    Wim C.J. Hop
    Footnotes
    † Deceased.
    Affiliations
    Department of Biostatistics, Erasmus MC, University Medical Center Rotterdam, The Netherlands
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  • Johannes J. Duvekot
    Correspondence
    Corresponding author at: Department of Obstetrics and Gynaecology, Division of Obstetrics and Prenatal Medicine, Erasmus MC, University Medical Center Rotterdam, Room SP-4458, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands. Tel.: +31 (0)10 7036538.
    Affiliations
    Department of Obstetrics and Gynaecology, Division of Obstetrics and Prenatal Medicine, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    Search for articles by this author
  • Author Footnotes
    † Deceased.
Published:January 06, 2023DOI:https://doi.org/10.1016/j.ejogrb.2023.01.007
Are troponin T levels in women with pre-eclampsia related to development of pulmonary oedema?
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      We found that elevated troponin T (TnT) in women with severe pre-eclampsia was associated with development of pulmonary oedema. Keepanasseril et al. evaluated serum biomarkers in severe pre-eclampsia [
      • Keepanasseril A.
      • Bharathi V.
      • Bobby Z.
      • Kar S.S.
      • Parameswaran S.
      • Pillai A.A.
      • et al.
      Serum biomarkers of maternal morbidity and adverse outcome in severe pre-eclampsia.
      Eur J Obstet Gynecol Reprod Biol. 2022; 270: 190-194
      ], and concluded that as well as oxidative stress biomarkers, endothelial dysfunction was also associated with pre-eclampsia. However, the clinical use of this in practice may be limited to detect patients with pre-eclampsia who are at risk of developing side effects [
      • Keepanasseril A.
      • Bharathi V.
      • Bobby Z.
      • Kar S.S.
      • Parameswaran S.
      • Pillai A.A.
      • et al.
      Serum biomarkers of maternal morbidity and adverse outcome in severe pre-eclampsia.
      Eur J Obstet Gynecol Reprod Biol. 2022; 270: 190-194
      ]. As such, we investigated whether TnT levels are associated with development of pulmonary oedema in women with pre-eclampsia.
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      References

        • Keepanasseril A.
        • Bharathi V.
        • Bobby Z.
        • Kar S.S.
        • Parameswaran S.
        • Pillai A.A.
        • et al.
        Serum biomarkers of maternal morbidity and adverse outcome in severe pre-eclampsia.
        Eur J Obstet Gynecol Reprod Biol. 2022; 270: 190-194
        View in Article
        • Hypertension in pregnancy
        Report of the American College of Obstetricians and Gynecologists’ Task Force on Hypertension in Pregnancy.
        Obstet Gynecol. 2013; 122: 1122-1131
        View in Article
        • Hamm C.W.
        • Goldmann B.U.
        • Heeschen C.
        • Kreymann G.
        • Berger J.
        • Meinertz T.
        Emergency room triage of patients with acute chest pain by means of rapid testing for cardiac troponin T or troponin I.
        N Engl J Med. 1997; 337: 1648-1653
        View in Article

      4. Christenson RH, Apple FS, Morgan DL, et al. Cardiac troponin I measurement with the ACCESS immunoassay system: analytical and clinical performance characteristics. Clin Chem 1998;44:52–60.

        View in Article

      5. Gajic O, Gropper MA, Hubmayr RD. Pulmonary edema after transfusion: how to differentiate transfusion-associated circulatory overload from transfusion-related acute lung injury. Crit Care Med 2006;34:S109–13.

        View in Article

      Article info

      Publication history

      Published online: January 06, 2023
      Accepted: January 5, 2023
      Received: September 30, 2022

      Publication stage

      In Press Journal Pre-Proof

      Identification

      DOI: https://doi.org/10.1016/j.ejogrb.2023.01.007

      Copyright

      © 2023 Elsevier B.V. All rights reserved.

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