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Aicardi-Goutières syndrome: The need for clinical vigilance in fetuses with sonographic features of congenital infection

Published:January 10, 2023DOI:https://doi.org/10.1016/j.ejogrb.2023.01.010
      Aicardi-Goutières syndrome (AGS) is a genetic disorder that mainly affects the brain, immune system and skin. Most affected newborns show no signs or symptoms. Within the first year of life, patients will develop an episode of severe brain dysfunction (encephalopathy) that is usually severe. We here describe a case of AGS mimicking a congenital infection in utero caused by variants in RNASEH2C.
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