Guest Editorial| Volume 90, ISSUE 1, P1-2, May 2000

Atrophie blanche

      Atrophie blanche or white atrophy is a disorder which is described in association with several diseases. It is predominantly localised on the lower leg, but can be localised on any part of the body. Clinical atrophie blanche is characterised by smooth, depressed, ivory white plaque in and around which numerous teleangiectatic capillaries are arrayed. It should not be confused with lichen sclerosis (which is often located on the vulva), scleroderma, malignant atrophic papulosis and scar formation. Histological difference between these disorders is very clear. In atrophie blanche a combination of avascular fields and dilated capillaries with tortuous loops are seen.
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        • Dahlbäck B.
        • Carlsson M.
        • Svensson P.J.
        Familial thrombofilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein C.
        Proc Natl Acad Sci USA. 1993; 90: 1004-1008
        • Rosing J.
        • Tans G.
        Effects of oral contraceptives on hemostasis and thrombosis.
        Am J Obstet Gynecol. 1999; 180: S375-S382
        • Maessen-Visch M.B.
        • Hamulyak K.
        • Tazelaar D.J.
        • et al.
        The prevalence of factor V Leiden mutation in patients with leg ulcers and venous insufficiency.
        Arch Dermatol. 1999; 135: 41-44
        • Brandjes D.P.M.
        • Büller H.R.
        • Heijboer H.
        • et al.
        Randomised trial of effect of compression stockings in patients with symptomatic proximal vein thrombosis.
        Lancet. 1997; 349: 759-762
        • Bollinger A.
        • Leu A.J.
        Evidence for microvascular thrombosis obtained by intravital fluorescence videomicroscopy.
        VASA. 1991; 20: 252-255
        • Maessen-Visch M.B.
        • Koedam M.I.
        • Hamulyak K.
        • Neumann H.A.M.
        Atrophie blanche, a review.
        Int J Dermatol. 1999; 38: 161-172